Pub Date : 2026-01-02DOI: 10.1016/j.eimce.2025.503036
Julio Zarco Rodríguez, Jaime Lora-Tamayo Morillo-Velarde, Laura Morata Ruiz, Irantzu Rosselló Taberna, Xavier Oleart Martínez
Introduction: The care of patients with severe bacterial infections presents clinical, organizational, and human challenges. This study proposes a system to objectively assess the quality of humanized care in this context.
Methods: Using a multidisciplinary approach, unmet needs were identified and five strategic lines, twenty subdimensions, and a set of evaluation indicators were defined. The proposal was validated through a pilot in two hospitals.
Results: The indicators were designed to be applicable in different hospital settings to assess aspects such as treatment, care coordination, and communication. The pilot confirmed the feasibility of implementation and their usefulness for improvement planning.
Conclusions: The proposed indicator system is a useful tool to support progress toward more humanized and objectively measurable care for patients with severe bacterial infections.
{"title":"Development of humanization indicators for the care of patients with severe bacterial infections: Design and validation.","authors":"Julio Zarco Rodríguez, Jaime Lora-Tamayo Morillo-Velarde, Laura Morata Ruiz, Irantzu Rosselló Taberna, Xavier Oleart Martínez","doi":"10.1016/j.eimce.2025.503036","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.503036","url":null,"abstract":"<p><strong>Introduction: </strong>The care of patients with severe bacterial infections presents clinical, organizational, and human challenges. This study proposes a system to objectively assess the quality of humanized care in this context.</p><p><strong>Methods: </strong>Using a multidisciplinary approach, unmet needs were identified and five strategic lines, twenty subdimensions, and a set of evaluation indicators were defined. The proposal was validated through a pilot in two hospitals.</p><p><strong>Results: </strong>The indicators were designed to be applicable in different hospital settings to assess aspects such as treatment, care coordination, and communication. The pilot confirmed the feasibility of implementation and their usefulness for improvement planning.</p><p><strong>Conclusions: </strong>The proposed indicator system is a useful tool to support progress toward more humanized and objectively measurable care for patients with severe bacterial infections.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503036"},"PeriodicalIF":0.0,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145897131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.eimce.2025.503055
Jaime R Torres, Wilmer Villamil Gómez, Octavio Arce García, Francisco Javier Membrillo de Novales
Mayaro virus (MAYV) and Oropouche virus (OROV) cause emerging infections in Latin America. They represent an increasing public health threat in this and other regions due to their geographic spread, rising case numbers, and the identification of complications and fatal cases. This review, developed by specialists from Latin America and Spain, addresses the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of both infections, aiming to provide valuable information for the diagnosis and management of these diseases based on updated scientific evidence. The diagnostic challenges are emphasized, particularly the clinical overlap with other arboviral infections, the lack of commercial diagnostic tools, and the urgent need for active epidemiological surveillance. The risk of undetected outbreaks is highlighted, along with the importance of including these viruses in clinical algorithms-especially in residents or travellers to endemic areas and, specifically for OROV, in pregnant women with suspected arboviral infection.
{"title":"Epidemiology, diagnosis and treatment of Mayaro and Oropouche virus infections: implication for clinical practice and public health.","authors":"Jaime R Torres, Wilmer Villamil Gómez, Octavio Arce García, Francisco Javier Membrillo de Novales","doi":"10.1016/j.eimce.2025.503055","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.503055","url":null,"abstract":"<p><p>Mayaro virus (MAYV) and Oropouche virus (OROV) cause emerging infections in Latin America. They represent an increasing public health threat in this and other regions due to their geographic spread, rising case numbers, and the identification of complications and fatal cases. This review, developed by specialists from Latin America and Spain, addresses the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of both infections, aiming to provide valuable information for the diagnosis and management of these diseases based on updated scientific evidence. The diagnostic challenges are emphasized, particularly the clinical overlap with other arboviral infections, the lack of commercial diagnostic tools, and the urgent need for active epidemiological surveillance. The risk of undetected outbreaks is highlighted, along with the importance of including these viruses in clinical algorithms-especially in residents or travellers to endemic areas and, specifically for OROV, in pregnant women with suspected arboviral infection.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503055"},"PeriodicalIF":0.0,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145897075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-02DOI: 10.1016/j.eimce.2025.503040
Jordi Martinez-Matencio, Inmaculada Palacios-Garcia, Eduardo Cantón-Puig, José Garnacho-Montero
{"title":"A rare case of purulent pericarditis secondary to Streptococcus constellatus due to contiguity of a liver lesion under study.","authors":"Jordi Martinez-Matencio, Inmaculada Palacios-Garcia, Eduardo Cantón-Puig, José Garnacho-Montero","doi":"10.1016/j.eimce.2025.503040","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.503040","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503040"},"PeriodicalIF":0.0,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145897080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503038
María Aznar , Mariana G. López , María José Torres , Eduardo Briones , Juan Francisco Medina , Verónica González-Galán
Introduction
Tuberculosis (TB) in the Virgen del Rocío university hospital health area, included in the Seville Health District, Spain, exceeds the rate of 17 cases/100,000 inhabitants. Within the Mycobacterium tuberculosis complex (MTBC), M. tuberculosis sensu stricto comprises seven phylogenetic lineages (L1–L4 and L7–L9). The objective of this work is to know the circulating lineages in the area.
Methods
Molecular typing and sequencing were performed to identify circulating lineages from 2015 to 2022.
Results
From 2015 to 2019, the following were identified: L4 (95.95%, n = 355), L2 (1.62%, n = 6), and L6 (1.08%, n = 4). From 2020 to 2022: L4 94.62% (n = 123); L1 1.5% (n = 2); L3 1.5% (n = 2) and L2 0.76% (n = 1).
Conclusions
The emergence of different lineages in our area and their recognition are key to contributing to disease control. These findings demonstrate the need to continue surveillance and apply sequencing to understand and control the dynamics of TB transmission.
{"title":"Identification of lineages and sublineages of the Mycobacterium tuberculosis complex using advanced molecular strategies and WGS in Seville, Spain (2015–2022)","authors":"María Aznar , Mariana G. López , María José Torres , Eduardo Briones , Juan Francisco Medina , Verónica González-Galán","doi":"10.1016/j.eimce.2025.503038","DOIUrl":"10.1016/j.eimce.2025.503038","url":null,"abstract":"<div><h3>Introduction</h3><div>Tuberculosis (TB) in the Virgen del Rocío university hospital health area, included in the Seville Health District, Spain, exceeds the rate of 17 cases/100,000 inhabitants. Within the <em>Mycobacterium tuberculosis</em> complex (MTBC), <em>M. tuberculosis sensu stricto</em> comprises seven phylogenetic lineages (L1–L4 and L7–L9). The objective of this work is to know the circulating lineages in the area.</div></div><div><h3>Methods</h3><div>Molecular typing and sequencing were performed to identify circulating lineages from 2015 to 2022.</div></div><div><h3>Results</h3><div>From 2015 to 2019, the following were identified: L4 (95.95%, n = 355), L2 (1.62%, n = 6), and L6 (1.08%, n = 4). From 2020 to 2022: L4 94.62% (n = 123); L1 1.5% (n = 2); L3 1.5% (n = 2) and L2 0.76% (n = 1).</div></div><div><h3>Conclusions</h3><div>The emergence of different lineages in our area and their recognition are key to contributing to disease control. These findings demonstrate the need to continue surveillance and apply sequencing to understand and control the dynamics of TB transmission.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503038"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145897096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503044
Iñaki Comas
{"title":"Increasing clinical and public health role of Mycobacterium tuberculosis genomics","authors":"Iñaki Comas","doi":"10.1016/j.eimce.2025.503044","DOIUrl":"10.1016/j.eimce.2025.503044","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503044"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145957848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503050
Juliana Esperalba , Maria Arnedo-Muñoz , Ariadna Rando-Segura , Ibai Los-Arcos , Eva Revilla-López , Aroa Gomez-Brey , Patricia Nadal-Barón , Ester Marquez-Algaba , Víctor Monforte , Alberto Sandiumenge , Nieves Larrosa , Tomàs Pumarola , Oscar Len , Andrés Antón
Introduction
Cytomegalovirus (CMV) remains a significant infectious complication in solid organ transplant recipients. Assessing cellular immunity through interferon-gamma (IFN-γ) release assays, such as QuantiFERON®-CMV (QTF-CMV), is useful for guiding prophylactic and therapeutic decisions. Although ELISA is the validated method for QTF-CMV, chemiluminescence immunoassay (CLIA) may offer technical advantages. This study aimed to evaluate the performance of the CLIA-based LIAISON® QuantiFERON®-TB Gold Plus assay in quantifying IFN-γ in QTF-CMV testing, compared to the ELISA-based QuantiFERON®-CMV assay.
Methods
A retrospective study was conducted on 169 stored plasma samples from 85 lung transplant recipients. IFN-γ was quantified using both ELISA (Qiagen®) and CLIA (DiaSorin®). Specific (CMV-NIL) and nonspecific (MIT-NIL) responses were compared using Pearson and Lin's concordance correlation coefficients, Bland–Altman analysis, and ROC curves. Diagnostic agreement was assessed using the Kappa index, sensitivity, specificity, and agreement rates.
Results
CLIA yielded significantly higher IFN-γ values than ELISA for CMV-NIL (+0.41 IU/mL) and MIT-NIL (+0.33 IU/mL). Strong correlation and concordance were observed (r and ρc >0.93). Diagnostic agreement reached 95.86% (Kappa = 0.913), with fewer indeterminate results in CLIA (3.55% vs 4.73%). The optimal CLIA cut-off was 0.2754 IU/mL, achieving 100% sensitivity and specificity compared to ELISA.
Conclusions
CLIA shows excellent agreement with ELISA in QTF-CMV testing and is a reliable and automatable alternative. Its implementation may improve laboratory workflows. Adjusting the cut-off is recommended for optimal diagnostic accuracy.
{"title":"Implementing CLIA for QuantiFERON®-CMV testing: Optimizing cellular immune response against cytomegalovirus","authors":"Juliana Esperalba , Maria Arnedo-Muñoz , Ariadna Rando-Segura , Ibai Los-Arcos , Eva Revilla-López , Aroa Gomez-Brey , Patricia Nadal-Barón , Ester Marquez-Algaba , Víctor Monforte , Alberto Sandiumenge , Nieves Larrosa , Tomàs Pumarola , Oscar Len , Andrés Antón","doi":"10.1016/j.eimce.2025.503050","DOIUrl":"10.1016/j.eimce.2025.503050","url":null,"abstract":"<div><h3>Introduction</h3><div>Cytomegalovirus (CMV) remains a significant infectious complication in solid organ transplant recipients. Assessing cellular immunity through interferon-gamma (IFN-γ) release assays, such as QuantiFERON®-CMV (QTF-CMV), is useful for guiding prophylactic and therapeutic decisions. Although ELISA is the validated method for QTF-CMV, chemiluminescence immunoassay (CLIA) may offer technical advantages. This study aimed to evaluate the performance of the CLIA-based LIAISON® QuantiFERON®-TB Gold Plus assay in quantifying IFN-γ in QTF-CMV testing, compared to the ELISA-based QuantiFERON®-CMV assay.</div></div><div><h3>Methods</h3><div>A retrospective study was conducted on 169 stored plasma samples from 85 lung transplant recipients. IFN-γ was quantified using both ELISA (Qiagen®) and CLIA (DiaSorin®). Specific (CMV-NIL) and nonspecific (MIT-NIL) responses were compared using Pearson and Lin's concordance correlation coefficients, Bland–Altman analysis, and ROC curves. Diagnostic agreement was assessed using the Kappa index, sensitivity, specificity, and agreement rates.</div></div><div><h3>Results</h3><div>CLIA yielded significantly higher IFN-γ values than ELISA for CMV-NIL (+0.41<!--> <!-->IU/mL) and MIT-NIL (+0.33<!--> <!-->IU/mL). Strong correlation and concordance were observed (<em>r</em> and <em>ρ</em><sub>c</sub> >0.93). Diagnostic agreement reached 95.86% (Kappa<!--> <!-->=<!--> <!-->0.913), with fewer indeterminate results in CLIA (3.55% vs 4.73%). The optimal CLIA cut-off was 0.2754<!--> <!-->IU/mL, achieving 100% sensitivity and specificity compared to ELISA.</div></div><div><h3>Conclusions</h3><div>CLIA shows excellent agreement with ELISA in QTF-CMV testing and is a reliable and automatable alternative. Its implementation may improve laboratory workflows. Adjusting the cut-off is recommended for optimal diagnostic accuracy.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503050"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145957888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503033
Irati Arregui García , Iñaki Beguiristain , Miguel Fernández-Huerta , Jesús Castilla , María Eugenia Portillo Bordonabe
Background
The aim of this study was to analyse the changes in the incidence of invasive pneumococcal disease (IPD) before, during, and after the SARS-CoV-2 pandemic.
Methods
Cases of IPD detected through active epidemiological surveillance in Navarre, Spain, from 2018 to 2024 were analysed. Incidence rates were compared across three periods: pre-pandemic (2018–2019), pandemic (2020–2022), and post-pandemic (2023–2024) overall and by age groups and serotypes
Results
From 2018 to 2024, a total of 437 IPD cases were diagnosed in Navarre. The incidence of IPD decreased from 11.6 to 5.6 cases per 100,000 persons during the pandemic period and return to 13.0 cases per 100,000 persons in the post-pandemic period. The incidence decreased across all age groups in both, serotypes included and not included in the 13-valent pneumococcal conjugate vaccine (PCV13). Serotype 3 was the most frequent in the three periods, representing 20.3% of all cases. In the post-pandemic period, 35.2% of cases were due to serotypes included in the PCV-13, 45.7% in the PCV-15 and 64.2% in the PCV-20.
Conclusions
During the SARS-CoV-2 pandemic, the incidence of IPD decreased across all age groups for both, PCV13-included and not included serotypes. In the post-pandemic period, incidence returned to pre-pandemic levels. Whole-genome sequencing techniques helped to serotyping of S. pneumoniae, and thus, complemented epidemiological surveillance.
{"title":"Invasive pneumococcal disease before, during and after the SARS-CoV-2 pandemic","authors":"Irati Arregui García , Iñaki Beguiristain , Miguel Fernández-Huerta , Jesús Castilla , María Eugenia Portillo Bordonabe","doi":"10.1016/j.eimce.2025.503033","DOIUrl":"10.1016/j.eimce.2025.503033","url":null,"abstract":"<div><h3>Background</h3><div>The aim of this study was to analyse the changes in the incidence of invasive pneumococcal disease (IPD) before, during, and after the SARS-CoV-2 pandemic.</div></div><div><h3>Methods</h3><div>Cases of IPD detected through active epidemiological surveillance in Navarre, Spain, from 2018 to 2024 were analysed. Incidence rates were compared across three periods: pre-pandemic (2018–2019), pandemic (2020–2022), and post-pandemic (2023–2024) overall and by age groups and serotypes</div></div><div><h3>Results</h3><div>From 2018 to 2024, a total of 437 IPD cases were diagnosed in Navarre. The incidence of IPD decreased from 11.6 to 5.6 cases per 100,000 persons during the pandemic period and return to 13.0 cases per 100,000 persons in the post-pandemic period. The incidence decreased across all age groups in both, serotypes included and not included in the 13-valent pneumococcal conjugate vaccine (PCV13). Serotype 3 was the most frequent in the three periods, representing 20.3% of all cases. In the post-pandemic period, 35.2% of cases were due to serotypes included in the PCV-13, 45.7% in the PCV-15 and 64.2% in the PCV-20.</div></div><div><h3>Conclusions</h3><div>During the SARS-CoV-2 pandemic, the incidence of IPD decreased across all age groups for both, PCV13-included and not included serotypes. In the post-pandemic period, incidence returned to pre-pandemic levels. Whole-genome sequencing techniques helped to serotyping of <em>S. pneumoniae,</em> and thus, complemented epidemiological surveillance.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503033"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145897137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503049
Verónica Andrade-Amaráz, José Pedro Elizalde-Díaz
Introduction
Dengue virus infection remains a major public health challenge in tropical regions, with heterogeneous progression to severe disease.
Methods
We conducted a prospective longitudinal study of 362 laboratory-confirmed dengue patients, stratified by sex and the presence of warning signs. Serial hematological, hepatic and renal markers were collected over 96 h (at 24 h, 48 h, 72 h, and 96 h after symptom onset) to analyze their dynamic evolution.
Results
Patients with warning signs persisting beyond 48 h exhibited progressive hematological and hepatic deterioration, unlike those without warning signs. This was characterized by progressively declining platelet and neutrophil counts, elevated hematocrit, and rising AST/ALT levels. These worsening trends were more pronounced in women, who also showed a higher prevalence of warning signs (32% vs 25% in men).
Conclusion
The persistence of warning signs beyond 48 h represents a clinically relevant threshold for hematological and hepatic deterioration, supporting the need for protocolized monitoring – including serial platelet counts, hematocrit, and liver enzymes – during this critical window to enable early intervention in high-risk patients.
{"title":"Dengue warning signs persisting post-48 h demand monitoring to avert severe complications","authors":"Verónica Andrade-Amaráz, José Pedro Elizalde-Díaz","doi":"10.1016/j.eimce.2025.503049","DOIUrl":"10.1016/j.eimce.2025.503049","url":null,"abstract":"<div><h3>Introduction</h3><div>Dengue virus infection remains a major public health challenge in tropical regions, with heterogeneous progression to severe disease.</div></div><div><h3>Methods</h3><div>We conducted a prospective longitudinal study of 362 laboratory-confirmed dengue patients, stratified by sex and the presence of warning signs. Serial hematological, hepatic and renal markers were collected over 96<!--> <!-->h (at 24<!--> <!-->h, 48<!--> <!-->h, 72<!--> <!-->h, and 96<!--> <!-->h after symptom onset) to analyze their dynamic evolution.</div></div><div><h3>Results</h3><div>Patients with warning signs persisting beyond 48<!--> <!-->h exhibited progressive hematological and hepatic deterioration, unlike those without warning signs. This was characterized by progressively declining platelet and neutrophil counts, elevated hematocrit, and rising AST/ALT levels. These worsening trends were more pronounced in women, who also showed a higher prevalence of warning signs (32% vs 25% in men).</div></div><div><h3>Conclusion</h3><div>The persistence of warning signs beyond 48<!--> <!-->h represents a clinically relevant threshold for hematological and hepatic deterioration, supporting the need for protocolized monitoring – including serial platelet counts, hematocrit, and liver enzymes – during this critical window to enable early intervention in high-risk patients.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503049"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145957852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.eimce.2025.503046
José Miguel Gómez Verdú , Sergio Alemán Belando
{"title":"Reply to “Factors associated with glucocorticoid dosing in treating patients with noncritical COVID-19 pneumonia: Insights from an artificial intelligence-based CT imaging analysis”","authors":"José Miguel Gómez Verdú , Sergio Alemán Belando","doi":"10.1016/j.eimce.2025.503046","DOIUrl":"10.1016/j.eimce.2025.503046","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 1","pages":"Article 503046"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145957890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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