三磷酸腺苷结合盒转运体 G5 和 G8 是人类心血管疾病的早期诊断工具。

Q4 Medicine Wiadomosci lekarskie Pub Date : 2024-01-01 DOI:10.36740/WLek202402111
Amina A B Al-Dejeli, Murtadha A Al-Mudhafar, Imad K A Al-Sabri
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引用次数: 0

摘要

研究目的目的:本研究旨在探讨血清中ABCG5和ABCG5在心血管疾病的正常和预期心脏主诉中作为个体早期诊断工具的作用:材料和方法:在私立临床医院采集100名健康人和100名疑似心血管疾病患者的病史和临床体征后,以纸质形式收集并记录数据,并通过ELISA读取器采集血清以测量ABCG5和ABCG5的活性,结果显示所有年龄组的ABCG5和ABCG5的活性均较高:结果:结果:男女患者在所有年龄段的ABCG5和ABCG5的活性与同龄人在同一时期的活性相比明显下降,因此研究结果表明,可以使用血清中ABCG5和ABCG5的活性作为动脉粥样硬化性心血管疾病的诊断工具:结论我们确定了胆固醇转运与心血管疾病风险相关的进一步探索领域,并得出结论:以G5和G8为主的三磷酸腺苷结合盒转运体的变化是人类心血管疾病的早期诊断工具。我们对营养胆固醇和心血管疾病威胁的进一步研究领域进行了关联,在纳入的试验中,健康成年人摄入了高剂量的膳食胆固醇。
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Adenosine triphosphate binding cassette transporters G5 and G8 early diagnostic tools for cardiovascular disease in human.

Objective: Aim: The current study was designed to investigate the role of ABCG5 and ABCG5 in serum with normal and expected cardiac complaints with CVDs as individual early diagnostic tools.

Patients and methods: Materials and Methods: Data was collected in paper form and recorded from 100 healthy personals and 100 personals suspected with CVS after take the case history and clinical signs in private clinical hospital and the serum was collected for measurements the activity of ABCG5 and ABCG5 by used ELISA reader and the results illustrated that activity of ABCG5 and ABCG5 in all aged groups.

Results: Results: Activity of ABCG5 and ABCG5 in all aged groups periods in patient person male and female significant decrease as compared with same age in same period of live, so that the researched depicted that can used the serum activity of ABCG5 and ABCG5 as a diagnostics tools for atherosclerotic cardiovascular disease.

Conclusion: Conclusions: We identified areas of further exploration on cholesterol transport related with CVD risk and concluded that changes in the Adenosine Triphosphate Binding Cassette transporters mainly G5 and G8 early diagnostic tools for cardiovascular disease in Human. We correlated areas of farther disquisition on nutrient cholesterol and CVD threat, in the included trials, healthy grown-ups consumed high doses of dietary cholesterol.

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来源期刊
Wiadomosci lekarskie
Wiadomosci lekarskie Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
482
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