基于曲线变换的实时临床数据髓鞘定量分析

Jemila S Jacily, Therese A Brintha
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摘要

从实时传统磁共振成像中分割髓鞘是医学领域一项有用而又具有挑战性的任务。在这项工作中,在应用适当的预处理方法后,从实时 T1 加权磁共振成像中分割出髓鞘。从传统磁共振成像(MRI)(如 T1 加权磁共振成像)中量化髓鞘是研究领域的一项创新而又具有挑战性的任务。在文献中,还没有任何研究能对传统磁共振成像中的髓鞘进行分割和量化。使用临床数据是一项要求极高的任务。直接从临床数据中分割和量化髓鞘是不可能的。有必要在分割前采用预处理程序。在这项任务中,分割前使用了基于 Curvelet 变换的动态拉伸自适应高斯陷波滤波。与其他图像增强方法相比,如果我们采用动态拉伸,那么分割的区域就会非常接近放射科医生计算出的数值。在这种情况下,分割准确率和其他指标也很高。计算分割后的髓鞘面积,并将其与放射科医生计算的值进行比较。在基于 Curvelet 变换的高斯陷波滤波和动态拉伸的情况下,其值更接近人工计算值。
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Curvelet transform based myelin quantification from real time clinical data

Myelin segmentation from real-time conventional MRI is a useful and challenging task in the medical field. In this work, myelin is segmented from real-time T1-weighted MRI after the application of suitable pre-processing methods. Myelin quantification from conventional magnetic resonance imaging (MRI) such as T1-weighted MRI is an innovative and challenging task in the research field. In the literature, no effort is accessible to segment and quantify the myelin from conventional MRI. Working with clinical data is an immensely demanding task. It is impossible to segment and quantify myelin directly from clinical data. It was necessary to employ pre-processing procedures before segmentation. In this task, Curvelet transform based adaptive Gaussian notch filtering with dynamic stretching is used before segmentation. Different image enhancement methods are compared, When compared to other image enhancement methods if we apply dynamic stretching then the segmented area is very nearer to the values calculated by the radiologists. The segmentation accuracy and other metrics also high in this case. The area from segmented myelin is calculated and the values are compared to the values calculated by the radiologist. The values are nearer to manual calculation in the case of Curvelet transform based adative Gaussian notch filtering with dynamic stretching.

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