Heng Li, Yilei Wu, Dan Feng, Quangui Jiang, Shengkai Li, Jie Rong, Ling Zhong, Ulrich Methner, Laura Baxter, Sascha Ott, Daniel Falush, Zhenpeng Li, Xiangyu Deng, Xin Lu, Yi Ren, Biao Kan, Zhemin Zhou
{"title":"欧美猪肉的集中工业化助长了肠炎沙门氏菌的全球传播","authors":"Heng Li, Yilei Wu, Dan Feng, Quangui Jiang, Shengkai Li, Jie Rong, Ling Zhong, Ulrich Methner, Laura Baxter, Sascha Ott, Daniel Falush, Zhenpeng Li, Xiangyu Deng, Xin Lu, Yi Ren, Biao Kan, Zhemin Zhou","doi":"10.1038/s43016-024-00968-1","DOIUrl":null,"url":null,"abstract":"Salmonella enterica causes severe food-borne infections through contamination of the food supply chain. Its evolution has been associated with human activities, especially animal husbandry. Advances in intensive farming and global transportation have substantially reshaped the pig industry, but their impact on the evolution of associated zoonotic pathogens such as S. enterica remains unresolved. Here we investigated the population fluctuation, accumulation of antimicrobial resistance genes and international serovar Choleraesuis transmission of nine pig-enriched S. enterica populations comprising more than 9,000 genomes. Most changes were found to be attributable to the developments of the modern pig industry. All pig-enriched salmonellae experienced host transfers in pigs and/or population expansions over the past century, with pigs and pork having become the main sources of S. enterica transmissions to other hosts. Overall, our analysis revealed strong associations between the transmission of pig-enriched salmonellae and the global pork trade. By analysing the genome of over 9,000 pig-associated isolates, this study shows that modernized agricultural systems have favoured the acquisition of antimicrobial resistance genes, population expansion and global transmission of pig-enriched Salmonella over the past century.","PeriodicalId":94151,"journal":{"name":"Nature food","volume":null,"pages":null},"PeriodicalIF":23.6000,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43016-024-00968-1.pdf","citationCount":"0","resultStr":"{\"title\":\"Centralized industrialization of pork in Europe and America contributes to the global spread of Salmonella enterica\",\"authors\":\"Heng Li, Yilei Wu, Dan Feng, Quangui Jiang, Shengkai Li, Jie Rong, Ling Zhong, Ulrich Methner, Laura Baxter, Sascha Ott, Daniel Falush, Zhenpeng Li, Xiangyu Deng, Xin Lu, Yi Ren, Biao Kan, Zhemin Zhou\",\"doi\":\"10.1038/s43016-024-00968-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Salmonella enterica causes severe food-borne infections through contamination of the food supply chain. Its evolution has been associated with human activities, especially animal husbandry. Advances in intensive farming and global transportation have substantially reshaped the pig industry, but their impact on the evolution of associated zoonotic pathogens such as S. enterica remains unresolved. Here we investigated the population fluctuation, accumulation of antimicrobial resistance genes and international serovar Choleraesuis transmission of nine pig-enriched S. enterica populations comprising more than 9,000 genomes. Most changes were found to be attributable to the developments of the modern pig industry. All pig-enriched salmonellae experienced host transfers in pigs and/or population expansions over the past century, with pigs and pork having become the main sources of S. enterica transmissions to other hosts. Overall, our analysis revealed strong associations between the transmission of pig-enriched salmonellae and the global pork trade. By analysing the genome of over 9,000 pig-associated isolates, this study shows that modernized agricultural systems have favoured the acquisition of antimicrobial resistance genes, population expansion and global transmission of pig-enriched Salmonella over the past century.\",\"PeriodicalId\":94151,\"journal\":{\"name\":\"Nature food\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":23.6000,\"publicationDate\":\"2024-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.nature.com/articles/s43016-024-00968-1.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature food\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s43016-024-00968-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature food","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43016-024-00968-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Centralized industrialization of pork in Europe and America contributes to the global spread of Salmonella enterica
Salmonella enterica causes severe food-borne infections through contamination of the food supply chain. Its evolution has been associated with human activities, especially animal husbandry. Advances in intensive farming and global transportation have substantially reshaped the pig industry, but their impact on the evolution of associated zoonotic pathogens such as S. enterica remains unresolved. Here we investigated the population fluctuation, accumulation of antimicrobial resistance genes and international serovar Choleraesuis transmission of nine pig-enriched S. enterica populations comprising more than 9,000 genomes. Most changes were found to be attributable to the developments of the modern pig industry. All pig-enriched salmonellae experienced host transfers in pigs and/or population expansions over the past century, with pigs and pork having become the main sources of S. enterica transmissions to other hosts. Overall, our analysis revealed strong associations between the transmission of pig-enriched salmonellae and the global pork trade. By analysing the genome of over 9,000 pig-associated isolates, this study shows that modernized agricultural systems have favoured the acquisition of antimicrobial resistance genes, population expansion and global transmission of pig-enriched Salmonella over the past century.