Yee-Lam E. Chan MD, Wang-Sheng Lin MD, Hui-Chen Lai MS, Chih-Yuan Hung MD, Mao-Hsuan Huang MD
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引用次数: 0
摘要
背景：孤立的阻力训练（RT）对老年精神分裂症患者认知功能的影响尚未得到充分研究。本研究调查了为期 12 周的 POWER 康复（一种新型 RT 方案）对患有精神分裂症且身体虚弱的老年患者认知功能的影响：32名患有精神分裂症且身体虚弱的老年人被纳入研究，并随机接受为期12周、每周两次的POWER康复训练，或不接受附加训练。认知功能通过小型精神状态检查（MMSE）、数字符号替换测试、颜色追踪任务（CTT）和数字跨度任务（DST）进行评估。体能通过步行速度和手部握力进行评估。采用广义估计方程比较组间训练前后的结果：结果：组间分析显示，与对照组相比，干预组的 CTT1 和手部握力明显提高。分组分析显示，干预组在接受 12 周的 POWER 康复训练后，CTT1 的表现明显改善（时间，P 结论：POWER 康复训练是一种有效的康复训练方法：对患有精神分裂症且体弱的老年患者进行为期 12 周的 POWER 康复训练是安全可行的，而且可能对身体和认知功能的某些方面有益。
Changes in cognitive function after a 12-week POWER rehabilitation in older adults with schizophrenia and frailty
Background
The effectiveness of isolated resistance training (RT) on cognitive function among older adults with schizophrenia is insufficiently investigated. This study investigated the effectiveness of 12-weeks POWER rehabilitation, a novel RT regimen, on cognitive function among older patients with schizophrenia and frailty.
Methods
Thirty-two older adults with schizophrenia and frailty were enrolled and randomized to receive either a 12-week, twice weekly POWER rehabilitation, or without add-on training. Cognitive functioning was assessed using mini-mental state examination (MMSE), digit symbol substitution test, color trail task (CTT), and digit span task (DST). Physical performance was assessed by walking speed and hand grip strength. The generalized estimating equations was used to compare pre- and post-training outcome measure between groups.
Results
Between-group analysis revealed significant improvement in CTT1 and hand grip strength in the intervention group compared to the controls. Subgroup analyses showed CTT1 performance significantly improved after 12 weeks of POWER rehabilitation in the intervention group (time, p < .001), independent of age, educational level, global cognition, depressive symptoms, and psychotropic medication use. Increased hand grip strength was significantly associated with improved performance in MMSE, CTT1, and DST forward at study endpoint.
Conclusion
A 12-week POWER rehabilitation for older patients with schizophrenia and frailty is safe and feasible, and may benefit physical and some domains of cognitive functioning.
期刊介绍：
Asia-Pacific Psychiatry is an international psychiatric journal focused on the Asia and Pacific Rim region, and is the official journal of the Pacific Rim College of Psychiatrics. Asia-Pacific Psychiatry enables psychiatric and other mental health professionals in the region to share their research, education programs and clinical experience with a larger international readership. The journal offers a venue for high quality research for and from the region in the face of minimal international publication availability for authors concerned with the region. This includes findings highlighting the diversity in psychiatric behaviour, treatment and outcome related to social, ethnic, cultural and economic differences of the region. The journal publishes peer-reviewed articles and reviews, as well as clinically and educationally focused papers on regional best practices. Images, videos, a young psychiatrist''s corner, meeting reports, a journal club and contextual commentaries differentiate this journal from existing main stream psychiatry journals that are focused on other regions, or nationally focused within countries of Asia and the Pacific Rim.
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