Jiangbo Ying, Qian Hui Chew, Tian-Mei Si, Roy Abraham Kallivayalil, Andi J Tanra, Amir Hossein Jalali Nadoushan, Kok Yoon Chee, Afzal Javed, Pornjira Pariwatcharakul, Seon-Cheol Park, Shih-Ku Lin, Kuan-Lun Huang, Toshiya Inada, Sandeep Grover, Yu-Tao Xiang, Norman Sartorius, Naotaka Shinfuku, Takahiro A Kato, Ross J Baldessarini, Kang Sim
Introduction: Previous studies of antidepressant prescribing patterns largely were limited to a single location or time, and very few involved Asia. This Asian Psychotropic Prescription Patterns Consortium study investigated pharmacoepidemiologic trends and factors associated with use and dosing of newer antidepressants across 12 Asian sites in 2003, 2013, and 2023.
Methods: Data from each site included demographic, treatment setting, clinical features, and type and dosage of antidepressants prescribed. Sociodemographic and clinical variables were examined using univariate methods, followed by multivariable logistic and linear modeling.
Results: Of 8357 adult participants (59.8% female), 82.8% received at least one modern antidepressant. Use of these drugs was strongly associated with more recent year, younger age, inpatient status, and affective or anxiety-related disorders. Higher daily antidepressant doses were associated with inpatient status, male gender, more recent year, and younger age.
Discussion: This large, multisite study provides a two-decade overview of evolving antidepressant-prescribing patterns in 12 Asian sites and highlights patient characteristics associated with prescription of newer antidepressants and their dosage. Needed are further studies of psychotropic prescribing practices related to specific illness subtypes and their impact on psychosocial functioning over time among Asian patients.
{"title":"Pharmacoepidemiologic Trends and Factors Associated With Use and Dosing of Newer Antidepressants in 8357 Patients Across Asia: A Two-Decade Perspective.","authors":"Jiangbo Ying, Qian Hui Chew, Tian-Mei Si, Roy Abraham Kallivayalil, Andi J Tanra, Amir Hossein Jalali Nadoushan, Kok Yoon Chee, Afzal Javed, Pornjira Pariwatcharakul, Seon-Cheol Park, Shih-Ku Lin, Kuan-Lun Huang, Toshiya Inada, Sandeep Grover, Yu-Tao Xiang, Norman Sartorius, Naotaka Shinfuku, Takahiro A Kato, Ross J Baldessarini, Kang Sim","doi":"10.1111/appy.70017","DOIUrl":"https://doi.org/10.1111/appy.70017","url":null,"abstract":"<p><strong>Introduction: </strong>Previous studies of antidepressant prescribing patterns largely were limited to a single location or time, and very few involved Asia. This Asian Psychotropic Prescription Patterns Consortium study investigated pharmacoepidemiologic trends and factors associated with use and dosing of newer antidepressants across 12 Asian sites in 2003, 2013, and 2023.</p><p><strong>Methods: </strong>Data from each site included demographic, treatment setting, clinical features, and type and dosage of antidepressants prescribed. Sociodemographic and clinical variables were examined using univariate methods, followed by multivariable logistic and linear modeling.</p><p><strong>Results: </strong>Of 8357 adult participants (59.8% female), 82.8% received at least one modern antidepressant. Use of these drugs was strongly associated with more recent year, younger age, inpatient status, and affective or anxiety-related disorders. Higher daily antidepressant doses were associated with inpatient status, male gender, more recent year, and younger age.</p><p><strong>Discussion: </strong>This large, multisite study provides a two-decade overview of evolving antidepressant-prescribing patterns in 12 Asian sites and highlights patient characteristics associated with prescription of newer antidepressants and their dosage. Needed are further studies of psychotropic prescribing practices related to specific illness subtypes and their impact on psychosocial functioning over time among Asian patients.</p>","PeriodicalId":8618,"journal":{"name":"Asia‐Pacific Psychiatry","volume":"18 1","pages":"e70017"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Autonomy in End-Of-Life Dementia Care: Cultural and Ethical Perspectives From Japan.","authors":"Kae Ito, Narei Hong, Huali Wang","doi":"10.1111/appy.70015","DOIUrl":"10.1111/appy.70015","url":null,"abstract":"","PeriodicalId":8618,"journal":{"name":"Asia‐Pacific Psychiatry","volume":"18 1","pages":"e70015"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12967681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Shuen Sheng Fung, Yoshinori Cho, Young-Sook Kwak
{"title":"ACONAMI: A Case for Asian Mental Health Transformation.","authors":"Daniel Shuen Sheng Fung, Yoshinori Cho, Young-Sook Kwak","doi":"10.1111/appy.70016","DOIUrl":"https://doi.org/10.1111/appy.70016","url":null,"abstract":"","PeriodicalId":8618,"journal":{"name":"Asia‐Pacific Psychiatry","volume":"18 1","pages":"e70016"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}