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A Predictive Nomogram for Suicide Attempts in Chinese Adolescents With Both Non-Suicidal Self-Injury and Suicidal Ideation
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-04-23 DOI: 10.1111/appy.70003
Yi-Hui Liu, Ming Chen, Hao-Zhang Huang, Jia-Rong Liang, Yong-Yi He, Jia-Hui Hu, Ting-Ting Zhang, Fu-Jun Jia, Cai-Lan Hou

Introduction

Non-suicidal self-injury (NSSI) and suicidal ideation (SI) are prevalent and co-occurring among adolescents, serving as critical predictors of suicide. This study aimed to develop a predictive model and nomogram for suicide attempts (SA) in Chinese adolescents with mood disorders exhibiting NSSI and SI.

Methods

Data were collected from 134 participants. Predictors were selected via LASSO regression from data collected using the Self-Injurious Thoughts and Behaviors Interview-Revised and self-report scales, followed by multivariate logistic regression to build the nomogram. Model performance was assessed through discriminatory ability, calibration curves, and clinical decision analysis.

Results

Adolescents with SA history had fewer education years, higher prevalence and future likelihood of self-injurious thoughts and behaviors, earlier NSSI onset, more frequent and severe NSSI, and more intense and persistent SI compared to those without SA. Three key predictors for SA were identified: NSSI emotion regulation scores, average SI persistence duration, and history of interrupted attempts. The developed nomogram exhibited robust predictive accuracy with an AUC of 0.756.

Discussion

This study presents a predictive model for suicide risk in adolescents with mood disorders exhibiting NSSI and SI. The model demonstrates high predictive accuracy and clinical applicability, offering a practical tool for clinicians to prioritize high-risk cases and guide personalized interventions.

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引用次数: 0
Sexsomnia-Like Behaviors Associated With Zolpidem
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-02-25 DOI: 10.1111/appy.70002
Hui-Yuan Liao, Huang-Chi Lin
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引用次数: 0
Emergence of a New Threat in East Asia: Severe Agitation and Suicide Attempts Linked to Etomidate-Infused E-Cigarettes
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-02-13 DOI: 10.1111/appy.70001
Chun-I Liu, I-Ming Chen, Szu-Yung Wang, Chi Chen
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引用次数: 0
A Comparative Analysis of Neurological Soft Signs and Emotional Intelligence in Rapid Cycling and Non-Rapid Cycling Bipolar Disorder 快速循环与非快速循环双相情感障碍的神经软体征及情绪智力比较分析
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-11-28 DOI: 10.1111/appy.70000
Feng Yingying, Yang Bo, Zhao Jun

Background

Rapid cycling (RC) is a special subtype of bipolar disorder (BD). Previous studies have rarely involved the investigation of neurological soft signs (NSS) and emotional intelligence (EI) in rapid cycling patients.

Object

This study aims to compare the differences in NSS and EI between patients with RC and non-rapid cycling (NRC) in BD.

Methods

The Cambridge Neurological Inventory and The Mayer–Salovey–Caruso Emotional Intelligence Test were used to assess the NSS and EI levels of euthymic patients with BD and healthy controls (HC). Patients were divided into RC and NRC groups.

Results

In terms of NSS, both the RC and NRC groups scored significantly higher than the HC group in the Motor coordination subdomain and total scores. In the Sensory integration subdomain, there was a significant trend of RC group scoring higher than the NRC group, which in turn scored higher than the HC group. In terms of EI, there was a trend of RC group scoring lower than the NRC group, which scored lower than the HC group in the understanding emotions subdomain and MSCEIT total score. In the managing emotions subdomain, the RC group scored lower than the HC group.

Conclusion

Compared to the NRC group, the RC group exhibited higher NSS levels, mainly manifesting in more severe sensory integration impairment. The RC group scored lower in EI, primarily reflected in understanding and managing emotions, and the managing emotions subdomain may serve as a more sensitive indicator to distinguish between the two groups.

快速循环(RC)是双相情感障碍(BD)的一种特殊亚型。以往的研究很少涉及对快速循环患者的神经软体征(NSS)和情绪智力(EI)的调查。目的比较BD患者与非快速循环(NRC)患者NSS和EI水平的差异。方法采用剑桥神经量表和Mayer-Salovey-Caruso情绪智力测验评估健康BD患者和健康对照(HC)的NSS和EI水平。患者分为RC组和NRC组。结果在NSS方面,RC组和NRC组在运动协调子域和总分上均显著高于HC组。在感觉统合子域上,RC组得分高于NRC组,NRC组得分又高于HC组。在情商方面,RC组得分低于NRC组,NRC组在理解情绪子领域和MSCEIT总分上得分低于HC组。在情绪管理子领域,RC组得分低于HC组。结论与NRC组相比,RC组NSS水平较高,主要表现为感觉统合障碍加重。RC组的EI得分较低,主要体现在理解和管理情绪方面,情绪管理子域可能是区分两组的一个更敏感的指标。
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引用次数: 0
Cross-Cultural Differences in the Pathways to Internet Gaming Disorder 导致网络游戏障碍的跨文化差异。
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-10 DOI: 10.1111/appy.12565
Peter K. H. Chew, Patrick K. F. Lin, Yong Jie Yow

Background

No research to date has examined cross-cultural differences in the pathways to internet gaming disorder (IGD). The current study aimed to address this limitation by examining the relationships between nationality (Singaporeans vs. Australians), culture orientation, gaming motivations, and IGD.

Methods

Participants were 101 Singaporeans (55.4% males) and 98 Australians (52.0% males). They completed the Culture Orientation Scale, the Motives for Online Gaming Questionnaire, and the Internet Gaming Disorder Scale-Short-Form.

Results

A series of mediational analyses showed that Singaporeans tend to be more collectivistic (both horizontally and vertically). In turn, this culture orientation motivates them to play games for social reasons, increasing the risk for IGD. In contrast, Australians tend to be more individualistic (vertically only). In turn, this culture orientation motivates them to play games for competitive reasons, increasing the risk for IGD.

Conclusion

Limitations include the use of samples from two countries only, precluding a generalization of the results. Future research directions include examining the role of game genres as a mediator in the nationality-IGD relationship.

背景:迄今为止,还没有研究探讨过网络游戏障碍(IGD)的跨文化差异。本研究旨在通过考察国籍(新加坡人与澳大利亚人)、文化取向、游戏动机和 IGD 之间的关系来解决这一局限性:参与者包括 101 名新加坡人(55.4% 为男性)和 98 名澳大利亚人(52.0% 为男性)。他们填写了文化取向量表、网络游戏动机问卷和网络游戏障碍量表-简表:一系列中介分析表明,新加坡人更倾向于集体主义(横向和纵向)。反过来,这种文化取向促使他们出于社交原因玩游戏,从而增加了患 IGD 的风险。相比之下,澳大利亚人更倾向于个人主义(仅纵向)。反过来,这种文化取向促使他们出于竞争原因玩游戏,从而增加了患 IGD 的风险:研究的局限性包括研究样本仅来自两个国家,因此无法将研究结果普遍化。未来的研究方向包括研究游戏类型在民族-IGD 关系中的中介作用。
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引用次数: 0
Bipolar disorder and oxidative stress: A bibliometric perspective 躁郁症与氧化应激:文献计量学视角。
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-08-13 DOI: 10.1111/appy.12564
Zhen Gui PhD, Qinge Zhang MD, Sha Sha MD, Xiao-Hong Li MD, Zhaohui Su PhD, Teris Cheung PhD, Xi-Ling Cui PhD, Gabor S. Ungvari MD, PhD, Katrine K. Wong PhD, Chee H. Ng MBBS, MD, Feng Yuan MD, Yu-Tao Xiang MD, PhD

Objective

Accumulating evidence indicates that oxidative stress and the disruption of antioxidant defenses play an important role in the neurobiology of bipolar disorder (BD). Studies have found that increased oxidative stress may be associated with cell apoptosis and neuronal damage in BD patients. Hence, this study explored the research field related to BD and oxidative stress from a bibliometrics perspective.

Methods

Literature search and relevant data retrieval based on the Web of Sciences Core Collection (WoSCC). R software (version 4.2.2), VOSviewer software (version 1.6.18), and CiteSpace (version 6.1.6) were used in this bibliometric analysis.

Results

A total of 2081 publications related to BD and oxidative stress were published between 1986 and 2024. Bipolar Disorders was the journal that had the most publications in this area (72; 3.46%; IF = 5.9), while the United States (1285; 61.7%) and the University of Toronto (377; 18.1%) were the most productive country and institution, respectively. Apart from “oxidative stress” and “bipolar disorder,” the most frequently used keywords were “schizophrenia,” “prefrontal cortex,” and “nitric oxide.”

Conclusions

The growing number of publications related to BD and oxidative stress in recent years highlights the importance of this research field. Hot topics in research related to BD and oxidative stress included animal experiments and molecular mechanisms, psychiatric-related inflammation and biomarkers, neurodegenerative diseases, and metabolism. Furthermore, the biological mechanisms of BD, particularly biomarkers and inflammation, may be the emerging research priority area in the future.

目的:越来越多的证据表明,氧化应激和抗氧化防御系统的破坏在双相情感障碍(BD)的神经生物学中起着重要作用。研究发现,氧化应激的增加可能与双相情感障碍患者的细胞凋亡和神经元损伤有关。因此,本研究从文献计量学的角度探讨了与双相情感障碍和氧化应激相关的研究领域:文献检索和相关数据检索基于 Web of Sciences Core Collection (WoSCC)。文献计量学分析使用了 R 软件(4.2.2 版)、VOSviewer 软件(1.6.18 版)和 CiteSpace(6.1.6 版):结果:1986 年至 2024 年间,共发表了 2081 篇与 BD 和氧化应激相关的论文。双相情感障碍》是该领域发表论文最多的期刊(72篇;3.46%;IF=5.9),而美国(1285篇;61.7%)和多伦多大学(377篇;18.1%)分别是发表论文最多的国家和机构。除 "氧化应激 "和 "双相情感障碍 "外,最常使用的关键词是 "精神分裂症"、"前额叶皮质 "和 "一氧化氮":近年来,与躁狂症和氧化应激相关的论文数量不断增加,凸显了这一研究领域的重要性。与 BD 和氧化应激相关的研究热点包括动物实验和分子机制、精神相关炎症和生物标志物、神经退行性疾病和新陈代谢。此外,BD 的生物学机制,尤其是生物标志物和炎症,可能是未来新兴的研究重点领域。
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引用次数: 0
Optimizing esketamine clinic implementation: Insights from Taiwan's mental health framework 优化艾司氯胺酮诊所的实施:台湾心理健康框架的启示。
IF 2.8 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-08-05 DOI: 10.1111/appy.12563
Lien-Chung Wei MD, MPH, Li-Fen Chen MD, MPH
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引用次数: 0
Letter to the editor—Reflections on “Total valproate versus free valproate in therapeutic drug monitoring for bipolar disorder: A cross-sectional study” 致编辑的信--对 "丙戊酸总量与游离丙戊酸在双相情感障碍治疗药物监测中的对比:一项横断面研究"。
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-06-17 DOI: 10.1111/appy.12562
Lien-Chung Wei MD, MPH, Happy Kuy-Lok Tan MD, MPH, MHS
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引用次数: 0
Harnessing AI as an enabler for access to mental health care services 利用人工智能作为获得心理保健服务的推动力。
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-10 DOI: 10.1111/appy.12557
Aaradhana Rukadikar MBA (HR), Komal Khandelwal PhD
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引用次数: 0
Changes in cognitive function after a 12-week POWER rehabilitation in older adults with schizophrenia and frailty 对患有精神分裂症且体弱的老年人进行为期 12 周的 POWER 康复治疗后认知功能的变化。
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-05-10 DOI: 10.1111/appy.12556
Yee-Lam E. Chan MD, Wang-Sheng Lin MD, Hui-Chen Lai MS, Chih-Yuan Hung MD, Mao-Hsuan Huang MD

Background

The effectiveness of isolated resistance training (RT) on cognitive function among older adults with schizophrenia is insufficiently investigated. This study investigated the effectiveness of 12-weeks POWER rehabilitation, a novel RT regimen, on cognitive function among older patients with schizophrenia and frailty.

Methods

Thirty-two older adults with schizophrenia and frailty were enrolled and randomized to receive either a 12-week, twice weekly POWER rehabilitation, or without add-on training. Cognitive functioning was assessed using mini-mental state examination (MMSE), digit symbol substitution test, color trail task (CTT), and digit span task (DST). Physical performance was assessed by walking speed and hand grip strength. The generalized estimating equations was used to compare pre- and post-training outcome measure between groups.

Results

Between-group analysis revealed significant improvement in CTT1 and hand grip strength in the intervention group compared to the controls. Subgroup analyses showed CTT1 performance significantly improved after 12 weeks of POWER rehabilitation in the intervention group (time, p < .001), independent of age, educational level, global cognition, depressive symptoms, and psychotropic medication use. Increased hand grip strength was significantly associated with improved performance in MMSE, CTT1, and DST forward at study endpoint.

Conclusion

A 12-week POWER rehabilitation for older patients with schizophrenia and frailty is safe and feasible, and may benefit physical and some domains of cognitive functioning.

背景:孤立的阻力训练(RT)对老年精神分裂症患者认知功能的影响尚未得到充分研究。本研究调查了为期 12 周的 POWER 康复(一种新型 RT 方案)对患有精神分裂症且身体虚弱的老年患者认知功能的影响:32名患有精神分裂症且身体虚弱的老年人被纳入研究,并随机接受为期12周、每周两次的POWER康复训练,或不接受附加训练。认知功能通过小型精神状态检查(MMSE)、数字符号替换测试、颜色追踪任务(CTT)和数字跨度任务(DST)进行评估。体能通过步行速度和手部握力进行评估。采用广义估计方程比较组间训练前后的结果:结果:组间分析显示,与对照组相比,干预组的 CTT1 和手部握力明显提高。分组分析显示,干预组在接受 12 周的 POWER 康复训练后,CTT1 的表现明显改善(时间,P 结论:POWER 康复训练是一种有效的康复训练方法:对患有精神分裂症且体弱的老年患者进行为期 12 周的 POWER 康复训练是安全可行的,而且可能对身体和认知功能的某些方面有益。
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引用次数: 0
期刊
Asia‐Pacific Psychiatry
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