基于多反应 PNIPAM-PEGDA 水凝胶成分的仿生含羞草软机器人。

IF 2.6 4区 工程技术 Q2 BIOCHEMICAL RESEARCH METHODS Biomicrofluidics Pub Date : 2024-05-01 DOI:10.1063/5.0203482
Wenguang Yang, Xiaowen Wang, Xiangyu Teng, Zezheng Qiao, Haibo Yu, Zheng Yuan
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引用次数: 0

摘要

变形在自然生物的生存中起着至关重要的作用。其中一个例子是,植物通过变形来面向太阳,以获得充足的阳光照射,从而通过光合作用产生养分。从大自然中汲取灵感,研究人员一直在探索开发三维可变形材料。然而,制造可变形水凝胶的传统方法依赖于复杂的技术,这限制了它们的潜在应用。在这项研究中,我们模拟在植物组织中观察到的应力变化,从二维材料中创造出三维结构。利用紫外线固化技术,我们创建了一种带有微通道的单层聚(N-异丙基丙烯酰胺)水凝胶片材,这种水凝胶在受到刺激时会表现出不同的膨胀率。经过两步固化过程后,我们制备出了一种聚(N-异丙基丙烯酰胺)-聚乙二醇二丙烯酰胺双层结构,可以通过控制光和溶剂含量来改变其形状。在双层结构的基础上,我们制造出了一种能实现多种功能的双响应驱动仿生含羞草机器人。这种软机器人不仅能可逆地改变形状,还能在没有持续刺激的情况下保持特定形状。它因内应力而产生的可逆变形能力为生物医学和软机器人领域带来了广阔的应用前景。这项研究为开发可编程软材料提供了一个富有洞察力的框架。
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A bionic mimosa soft robot based on a multi-responsive PNIPAM-PEGDA hydrogel composition.

Deformation plays a vital role in the survival of natural organisms. One example is that plants deform themselves to face the sun for sufficient sunlight exposure, which allows them to produce nutrients through photosynthesis. Drawing inspiration from nature, researchers have been exploring the development of 3D deformable materials. However, the traditional approach to manufacturing deformable hydrogels relies on complex technology, which limits their potential applications. In this study, we simulate the stress variations observed in the plant tissue to create a 3D structure from a 2D material. Using UV curing technology, we create a single-layer poly(N-isopropylacrylamide) hydrogel sheet with microchannels that exhibit distinct swelling rates when subjected to stimulation. After a two-step curing process, we produce a poly(N-isopropylacrylamide)-polyethylene glycol diacrylatedouble-layer structure that can be manipulated to change its shape by controlling the light and solvent content. Based on the double-layer structure, we fabricate a dual-response driven bionic mimosa robot that can perform a variety of functions. This soft robot can not only reversibly change its shape but also maintain a specific shape without continuous stimulation. Its capacity for reversible deformation, resulting from internal stress, presents promising application prospects in the biomedical and soft robotics domain. This study delivers an insightful framework for the development of programmable soft materials.

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来源期刊
Biomicrofluidics
Biomicrofluidics 生物-纳米科技
CiteScore
5.80
自引率
3.10%
发文量
68
审稿时长
1.3 months
期刊介绍: Biomicrofluidics (BMF) is an online-only journal published by AIP Publishing to rapidly disseminate research in fundamental physicochemical mechanisms associated with microfluidic and nanofluidic phenomena. BMF also publishes research in unique microfluidic and nanofluidic techniques for diagnostic, medical, biological, pharmaceutical, environmental, and chemical applications. BMF offers quick publication, multimedia capability, and worldwide circulation among academic, national, and industrial laboratories. With a primary focus on high-quality original research articles, BMF also organizes special sections that help explain and define specific challenges unique to the interdisciplinary field of biomicrofluidics. Microfluidic and nanofluidic actuation (electrokinetics, acoustofluidics, optofluidics, capillary) Liquid Biopsy (microRNA profiling, circulating tumor cell isolation, exosome isolation, circulating tumor DNA quantification) Cell sorting, manipulation, and transfection (di/electrophoresis, magnetic beads, optical traps, electroporation) Molecular Separation and Concentration (isotachophoresis, concentration polarization, di/electrophoresis, magnetic beads, nanoparticles) Cell culture and analysis(single cell assays, stimuli response, stem cell transfection) Genomic and proteomic analysis (rapid gene sequencing, DNA/protein/carbohydrate arrays) Biosensors (immuno-assay, nucleic acid fluorescent assay, colorimetric assay, enzyme amplification, plasmonic and Raman nano-reporter, molecular beacon, FRET, aptamer, nanopore, optical fibers) Biophysical transport and characterization (DNA, single protein, ion channel and membrane dynamics, cell motility and communication mechanisms, electrophysiology, patch clamping). Etc...
期刊最新文献
Data-driven models for microfluidics: A short review. Applications of microfluidics in mRNA vaccine development: A review. Viscoelastic particle focusing and separation in a microfluidic channel with a cruciform section. Microfluidics for foodborne bacteria analysis: Moving toward multiple technologies integration. Wicking pumps for microfluidics.
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