COVID-19 时代的腹主动脉瘤破裂血管内修复术

Emily A. Grimsley MD, Haroon M. Janjua MS, Mark Asirwatham MD, Meagan D. Read MD, Paul C. Kuo MD, MS, MBA, Dean J. Arnaoutakis MD, Christopher A. Latz MD, MPH
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摘要

目的 COVID-19 大流行给医疗系统造成了巨大压力,导致护理流程发生改变(即治疗算法改变、供应短缺和人员短缺)。然而,COVID 和随之改变的护理流程对许多手术结果的影响还没有定性。尤其是腹主动脉瘤破裂(rAAA)的血管内主动脉修补术(EVAR)后的患者预后尚未得到充分报道。我们的目的是利用 COVID 患病率作为护理流程改变的替代指标,确定 COVID 阴性患者在 rAAA EVAR 术后预后的变化。方法利用疾病控制中心 COVID-19 数据,计算佛罗里达州每 3 个月季度的 COVID 死亡率。死亡率最高的三个季度和死亡率最低的三个季度分别被用来建立 COVID 重度时间框架和 COVID 轻度时间框架。2019 年的三个季度被用于 COVID 前的时间框架进行比较。使用国际疾病分类-10代码查询佛罗里达州卫生保健管理机构数据库,以确定在每个时间框架内接受EVAR的确诊为rAAA的患者。COVID阳性患者被排除在外。主要结果为院内死亡率、发病率和住院时间。通过10倍交叉验证的逐步线性回归和逻辑回归确定了哪些因素对主要结果影响最大。次要结果包括个别并发症发生率。手术量、人口统计学或合并症方面无明显差异,但 COVID-light时间段与COVID前时间段相比,有更多患者患有外周血管疾病(P = .01)。在单变量分析中,死亡率、住院时间和并发症在不同时间段没有明显差异。结论尽管在 COVID-19 大流行期间医疗系统的压力增大,但佛罗里达州的 rAAA EVAR 术后结果没有变化。这些结果表明,尽管在 COVID 期间医疗系统承受了巨大压力,但患者护理仍保持了 COVID 前的护理标准。
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Endovascular aortic repair for ruptured abdominal aortic aneurysm during the COVID-19 era

Objective

The COVID-19 pandemic caused significant stress on health care systems, leading to altered care processes (ie, altered treatment algorithms, supply shortages, and personnel shortages). However, the effect of COVID and subsequent altered care processes on many surgical outcomes has not been characterized. In particular, patient outcomes after endovascular aortic repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA) have not been well reported. Using COVID prevalence as a surrogate for altered processes of care, our aim is to determine changes in COVID-negative patient outcomes after EVAR for rAAA.

Methods

Using the Center for Disease Control COVID-19 data, COVID mortality per 3-month quarter was calculated in Florida. The quarters with the three highest mortality rates and three lowest mortality rates were used to establish COVID-heavy and COVID-light timeframes, respectively. Three quarters of 2019 were used for the pre-COVID timeframe for comparison. The Florida Agency for Health Care Administration database was queried using International Classification of Diseases-10 codes to identify patients diagnosed with rAAA who underwent EVAR during each timeframe. COVID-positive patients were excluded. Primary outcomes were in-hospital mortality, morbidity, and length of stay. Stepwise linear and logistic regression with 10-fold cross-validation determined which factors most impacted primary outcomes. Secondary outcomes included individual complication rates.

Results

A total of 316 patients were included. There were no significant differences in surgical volume, demographics, or comorbidities except that more patients had peripheral vascular disease in the COVID-light timeframe compared with the pre-COVID timeframe (P = .01). Mortality, length of stay, and complications were not significantly different per timeframe on univariable analysis. Regression confirmed that timeframe was not significantly associated with any primary outcome.

Conclusions

Despite increased stress on the health care system during the COVID-19 pandemic, outcomes after EVAR for rAAA were unchanged in Florida. These results imply that despite periods of COVID-heavy stress on the health care system, patient care was maintained at the pre-COVID standard of care.

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