北美城市野鼠和大鼠的 SARS-CoV-2 监控。

IF 2.2 3区环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES Ecohealth Pub Date : 2024-03-01 Epub Date: 2024-05-15 DOI:10.1007/s10393-024-01679-6

Lisa K F Lee, Chelsea G Himsworth, Natalie Prystajecky, Antonia Dibernardo, L Robbin Lindsay, Theresa M Albers, Rajeev Dhawan, Ken Henderson, Guy Mulder, Harveen K Atwal, Imara Beattie, Bruce K Wobeser, Michael H Parsons, Kaylee A Byers

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引用次数: 0

摘要

2020 年 7 月至 2021 年 6 月，对来自美国得克萨斯州、华盛顿州和加拿大不列颠哥伦比亚省的 248 只野生家鼠（Mus musculus）、鹿鼠（Peromyscus maniculatus）、褐鼠（Rattus norvegicus）和黑鼠（Rattus rattus）进行了 SARS-CoV-2 暴露和感染检测。两只棕色大鼠和 11 只家鼠的中和抗体在代用病毒中和试验中呈阳性，但在针对全长尖峰蛋白和核蛋白的多重荧光免疫测定 COVID-Plex 中呈阴性或不确定。口鼻咽拭子和粪便样本经 RT-qPCR 检测呈阴性，一只家鼠的粪便样本不确定。有必要继续监测野生啮齿动物中的 SARS-CoV-2 病毒。

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SARS-CoV-2 Surveillance of Wild Mice and Rats in North American Cities.

From July 2020 to June 2021, 248 wild house mice (Mus musculus), deer mice (Peromyscus maniculatus), brown rats (Rattus norvegicus), and black rats (Rattus rattus) from Texas and Washington, USA, and British Columbia, Canada, were tested for SARS-CoV-2 exposure and infection. Two brown rats and 11 house mice were positive for neutralizing antibodies using a surrogate virus neutralization test, but negative or indeterminate with the Multiplexed Fluorometric ImmunoAssay COVID-Plex, which targets full-length spike and nuclear proteins. Oro-nasopharyngeal swabs and fecal samples tested negative by RT-qPCR, with an indeterminate fecal sample in one house mouse. Continued surveillance of SARS-CoV-2 in wild rodents is warranted.

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来源期刊

Ecohealth 环境科学-环境科学

CiteScore

4.50

自引率

4.00%

发文量

审稿时长

>24 weeks

期刊介绍： EcoHealth aims to advance research, practice, and knowledge integration at the interface of ecology and health by publishing high quality research and review articles that address and profile new ideas, developments, and programs. The journal’s scope encompasses research that integrates concepts and theory from many fields of scholarship (including ecological, social and health sciences, and the humanities) and draws upon multiple types of knowledge, including those of relevance to practice and policy. Papers address integrated ecology and health challenges arising in public health, human and veterinary medicine, conservation and ecosystem management, rural and urban development and planning, and other fields that address the social-ecological context of health. The journal is a central platform for fulfilling the mission of the EcoHealth Alliance to strive for sustainable health of people, domestic animals, wildlife, and ecosystems by promoting discovery, understanding, and transdisciplinarity. The journal invites substantial contributions in the following areas: One Health and Conservation Medicine o Integrated research on health of humans, wildlife, livestock and ecosystems o Research and policy in ecology, public health, and agricultural sustainability o Emerging infectious diseases affecting people, wildlife, domestic animals, and plants o Research and practice linking human and animal health and/or social-ecological systems o Anthropogenic environmental change and drivers of disease emergence in humans, wildlife, livestock and ecosystems o Health of humans and animals in relation to terrestrial, freshwater, and marine ecosystems Ecosystem Approaches to Health o Systems thinking and social-ecological systems in relation to health o Transdiiplinary approaches to health, ecosystems and society.