与西班牙心房颤动和缺血性心脏病患者死亡率相关的变量

IF 3.9 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS European Heart Journal: Acute Cardiovascular Care Pub Date : 2024-05-09 DOI:10.1093/ehjacc/zuae036.108
E Minguez De La Guia, N Vallejo Calcerrada, M J Corbi Pascual, C Bonanad Lozano, P Cepas Guillen, A Cordero Fort, I Nunez Gil, M Thiscal Lopez, S Raposeiras Roubin, J L Ferreiro Gutierrez, E Moreno, F Diez Del Hoyo, A Ayesta, J A Perez Rivera, P Diez Villanueva
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Baseline, clinical, laboratory and echocardiographic characteristics were assessed, as well as the clinical management and the choice of antithrombotic treatment. We studied long-term mortality. Results 290 patients were included (mean age 77.7±9.7 years, 28% women). 84% of the patients were hypertensive, 42% diabetic, 69.7% dyslipidemic. The average comorbidity, characterized by the Charlson index, was 2.3±2. The average score on the CHADSVASC and HASBLED scales was 4.28±1.62 and 2.94±1, respectively. The clinical presentation of ischaemic heart disease was NSTEMI (45%), STEMI (22%) and stable angina (33%). 65.6% of patients underwent revascularisation, mostly percutaneously (92%). 42% of patients were discharged with triple therapy (double antiplatelet + anticoagulation), 30.1% with double therapy (antiplatelet + anticoagulation). After an average follow-up of 325±5.7 days, 35 patients (12%) died. 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引用次数: 0

摘要

无。导言:心房颤动(AF)和缺血性心脏病(IHD)的发病率随着年龄的增长而增加,在临床实践中是一种复杂且相对常见的情况。我们的目的是了解我国心房颤动和缺血性心脏病患者随访一年后与预后相关的变量。方法 这是一项观察性、前瞻性和多中心研究,研究对象包括西班牙的房颤和心肌梗死患者。我们评估了基线、临床、实验室和超声心动图特征,以及临床治疗和抗血栓治疗的选择。我们还对长期死亡率进行了研究。结果 共纳入 290 名患者(平均年龄为 77.7±9.7 岁,28% 为女性)。84%的患者患有高血压,42%患有糖尿病,69.7%患有血脂异常。合并症(以夏尔森指数为特征)的平均值为 2.3±2,CHADSVASC 和 HASBLED 量表的平均值分别为 4.28±1.62 和 2.94±1。缺血性心脏病的临床表现为非STEMI(45%)、STEMI(22%)和稳定型心绞痛(33%)。65.6%的患者接受了血管重建手术,其中大部分是经皮手术(92%)。42%的患者出院时接受了三联疗法(双联抗血小板+抗凝),30.1%的患者接受了双联疗法(抗血小板+抗凝)。平均随访 325±5.7 天后,35 名患者(12%)死亡。表中列出了随访期间与死亡率独立相关的变量(多变量分析)(在我们的研究中,肌酐、白细胞计数、肌钙蛋白升高、病变血管数量、心室功能和合并症是预测死亡率的因素)。结论 一系列简单变量的存在可确定心房颤动和心肌缺血患者在随访期间有更大的死亡风险。
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Variables associated with mortality in patients with atrial fibrillation and ischaemic heart disease in Spain
Funding Acknowledgements None. Introduction The prevalence of atrial fibrillation (AF) and ischaemic heart disease (IHD) increases with age, conditioning a complex and relatively frequent scenario in clinical practice. Our objective was to know the variables associated with prognosis in a cohort of patients with AF and IHD in our country after a year of follow-up. Methods An observational, prospective and multicentre study that included patients with AF and IHD in Spain. Baseline, clinical, laboratory and echocardiographic characteristics were assessed, as well as the clinical management and the choice of antithrombotic treatment. We studied long-term mortality. Results 290 patients were included (mean age 77.7±9.7 years, 28% women). 84% of the patients were hypertensive, 42% diabetic, 69.7% dyslipidemic. The average comorbidity, characterized by the Charlson index, was 2.3±2. The average score on the CHADSVASC and HASBLED scales was 4.28±1.62 and 2.94±1, respectively. The clinical presentation of ischaemic heart disease was NSTEMI (45%), STEMI (22%) and stable angina (33%). 65.6% of patients underwent revascularisation, mostly percutaneously (92%). 42% of patients were discharged with triple therapy (double antiplatelet + anticoagulation), 30.1% with double therapy (antiplatelet + anticoagulation). After an average follow-up of 325±5.7 days, 35 patients (12%) died. The variables independently associated (multivariate analysis) with mortality during follow-up are shown in the Table (creatinine, leukocyte count, troponin elevation, number of diseased vessels, ventricular function, and comorbidity were mortality predictors in our study). Conclusions The presence of a series of simple variables identifies patients with AF and IHD as having a greater risk of mortality during follow-up.Variables independentily associated AF
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来源期刊
CiteScore
8.50
自引率
4.90%
发文量
325
期刊介绍: The European Heart Journal - Acute Cardiovascular Care (EHJ-ACVC) offers a unique integrative approach by combining the expertise of the different sub specialties of cardiology, emergency and intensive care medicine in the management of patients with acute cardiovascular syndromes. Reading through the journal, cardiologists and all other healthcare professionals can access continuous updates that may help them to improve the quality of care and the outcome for patients with acute cardiovascular diseases.
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