开发具有抗菌特性的乳胶/氧化锌化合物,应用于生物医学工程

IF 3.1 Q2 MATERIALS SCIENCE, COMPOSITES Functional Composites and Structures Pub Date : 2024-05-12 DOI:10.1088/2631-6331/ad45a8
G Durango-Giraldo, C Zapata-Hernandez, J F Santa and R Buitrago-Sierra
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引用次数: 0

摘要

天然橡胶胶乳(NRL)是从橡胶树(Hevea brasiliensis)中提取的聚合物,已被用于多种生物医学应用,但不具有抗菌特性。在这项工作中,我们合成了两种不同形态的氧化锌纳米粒子,并以不同浓度添加到 NRL 中,以评估所生成化合物的抗菌特性。电子显微镜和 X 射线衍射的表征结果表明,两种纳米材料的纳米粒子分别呈球形(平均粒径为 69 ± 17 nm)和片状(平均粒径为 154 ± 46 nm),均为 Wurtzite 晶相。抗菌测试结果表明,这两种化合物对大肠杆菌有效,片状和球状纳米材料的细菌存活率分别降低了 90.3% 和 96.4%。对于金黄色葡萄球菌,两种情况下细菌的存活率都有所降低。球形纳米粒子的抗菌活性最强。
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Development of latex/zinc oxide compounds with antibacterial properties for applications in biomedical engineering
Natural rubber latex (NRL)—a polymer extracted from the rubber tree (Hevea brasiliensis)—has been used in multiple biomedical applications but does not have antibacterial properties. In this work, ZnO nanoparticles with two different morphologies were synthesized and added to NRL at different concentrations in order to evaluate the antibacterial properties of the resulting compounds. The characterization results obtained by electron microscopy and x-ray diffraction showed nanoparticles with spherical (mean size 69 ± 17 nm) and sheet morphology (mean size 154 ± 46 nm) with Wurtzite crystalline phase for both nanomaterials, respectively. The results of antibacterial tests showed that both compounds are effective against E. coli, and the reduction in bacterial viability was 90.3% and 96.4% for sheets and spherical nanomaterials, respectively. In the case of S. aureus, bacterial viability was reduced in both cases. The greatest antibacterial activity was evidenced in the nanoparticles with spherical morphology.
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来源期刊
Functional Composites and Structures
Functional Composites and Structures Materials Science-Materials Science (miscellaneous)
CiteScore
4.80
自引率
10.70%
发文量
33
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