作为最小模型的设计原则

IF 1.4 2区 哲学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Studies in History and Philosophy of Science Pub Date : 2024-05-15 DOI:10.1016/j.shpsa.2024.03.003
Wei Fang
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引用次数: 0

摘要

在这篇文章中,我建议把系统生物学中的设计原理视为最小模型,因为设计原理通常表现出普遍行为,而这些行为是具有不同内在机制的各种异质(生物和非生物)系统所共有的。本文讨论了系统生物学中一个著名的设计原理--积分反馈控制,表明它满足了一个模型成为最小模型的所有条件。这种方法具有重要的哲学意义:它不仅说明了设计原理是如何解释的,而且有助于澄清关于设计原理的一个争议,例如,设计原理是提供机械解释还是提供一种称为设计解释的独特解释。
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Design principles as minimal models

In this essay I suggest that we view design principles in systems biology as minimal models, for a design principle usually exhibits universal behaviors that are common to a whole range of heterogeneous (living and nonliving) systems with different underlying mechanisms. A well-known design principle in systems biology, integral feedback control, is discussed, showing that it satisfies all the conditions for a model to be a minimal model. This approach has significant philosophical implications: it not only accounts for how design principles explain, but also helps clarify one dispute over design principles, e.g., whether design principles provide mechanistic explanations or a distinct kind of explanations called design explanations.

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来源期刊
Studies in History and Philosophy of Science
Studies in History and Philosophy of Science 管理科学-科学史与科学哲学
CiteScore
2.50
自引率
10.00%
发文量
166
审稿时长
6.6 weeks
期刊介绍: Studies in History and Philosophy of Science is devoted to the integrated study of the history, philosophy and sociology of the sciences. The editors encourage contributions both in the long-established areas of the history of the sciences and the philosophy of the sciences and in the topical areas of historiography of the sciences, the sciences in relation to gender, culture and society and the sciences in relation to arts. The Journal is international in scope and content and publishes papers from a wide range of countries and cultural traditions.
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