Xiantao Ma*, Jing Yu, Feng Liu, Ying Zhou, Wenxin Man, Xiaoyu Yan and Yingying Zhu,
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The preparation of n-bromobutane is one of the required training items in Experimental Organic Chemistry for undergraduates. However, there are still drawbacks: the reaction process is not easy to monitor, and the yield of n-bromobutane is low (∼50%) in the available experimental protocols. In this improved experiment, the visual preparation of n-bromobutane was realized through the ingenious use of a Dean–Stark apparatus. Moreover, the postprocessing steps of the reaction were simplified: while the reaction was proceeding, separation and purification were conducted at the same time, thus leading to an increase in product yield (from ∼50% to ∼70%). As a result, the improved protocol provides conveniences for students to observe the reaction process intuitively and accurately by using the obvious stratification phenomenon in the Dean–Stark apparatus for visual teaching. Moreover, it also expands the scope of the use of the Dean–Stark apparatus and stimulates students’ interest in learning organic chemistry. The experiment has good cost-effectiveness and takes ∼3 class hours, which is fairly suitable to be widely used in undergraduate teaching.
期刊介绍:
The Journal of Chemical Education is the official journal of the Division of Chemical Education of the American Chemical Society, co-published with the American Chemical Society Publications Division. Launched in 1924, the Journal of Chemical Education is the world’s premier chemical education journal. The Journal publishes peer-reviewed articles and related information as a resource to those in the field of chemical education and to those institutions that serve them. JCE typically addresses chemical content, activities, laboratory experiments, instructional methods, and pedagogies. The Journal serves as a means of communication among people across the world who are interested in the teaching and learning of chemistry. This includes instructors of chemistry from middle school through graduate school, professional staff who support these teaching activities, as well as some scientists in commerce, industry, and government.