睡眠呼吸障碍的诊断和治疗过程

Karolina Maliszewska, Izabela Oleksak, Iwona Welian-Polus, Karolina Gendek, Wiktoria Wilanowska, Kamila Babkiewicz-Jahn, Justyna Matuszewska
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摘要

导言和目的 睡眠呼吸暂停是一种睡眠障碍,约影响 10%的成年人,由于症状不明确,不易被发现。本文献综述旨在分别介绍阻塞性睡眠呼吸暂停和中枢性睡眠呼吸暂停的症状,并整合有关发病机制和治疗方法的现有文献数据。材料和方法 使用 PubMed 和谷歌学术数据库进行文献综述。搜索标准包括睡眠呼吸暂停、阻塞性睡眠呼吸暂停治疗、中枢性睡眠呼吸暂停治疗等关键词。知识现状 涉及呼吸的睡眠障碍可分为阻塞性睡眠呼吸暂停(OSA)和中枢性睡眠呼吸暂停。前者与上呼吸道阻塞有关,后者则与髓质呼吸起搏器的呼吸发生器功能失常有关。症状没有特异性,因此诊断过程比较困难。然而,正确的诊断和治疗可以防止患者患上多种心血管疾病。治疗 OSA 的方法包括CPAP、减轻体重、改变睡眠姿势、支具和手术;对于 CSA:CPAP 和乙酰唑胺。结论 OSA 和 CSA 需要进一步研究,以便找到更精确的诊断和治疗方法,因为这些疾病的报告率仍然很低。值得注意的是,这些疾病容易引发中风等严重疾病。因此,开发新的治疗技术将有益于人们的健康。
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Diagnostic and therapeutic process of respiratory disorders during sleep
Introduction and purpose Sleep apnea is a disturbance of sleep that affects about 10% of adult population and is not easily detected due to unspecific symptoms. The aim of this literature review is to present, respectively, obstructive sleep apnea and central sleep apnea symptoms and integrate the available data in the literature regarding the pathogenesis and treatment methods. Materials and methods A review of literature was performed using PubMed and Google Scholar database. The search criteria included keywords such as sleep apnea, obstructive sleep apnea treatment, central sleep apnea treatment. State of knowledge Sleep disturbances that involve breathing can be categorized as obstructive sleep apnea (OSA) and central sleep apnea. First one is associated with the obstruction of the upper airways and the second one – with malfunctioning breathing generator in the pontomedullary breathing pacemaker. Symptoms are unspecific which makes diagnostic process difficult. However, the right diagnosis and treatment may prevent patients from developing many cardiovascular diseases. Treatment options for OSA include: CPAP, reducing body weight, changing sleep position, braces and surgeries; for CSA: CPAP and acetazolamide. Conclusions OSA and CSA need to be further investigated in order to find more precise ways of diagnosis and treatment, as these diseases remain underreported. It is worth noting, that these conditions predispose to serious diseases, e.g. stroke. Therefore, developing new treatment techniques would beneficial for the health of population.
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