具有不同扩散率的延迟时空宿主-病原体感染模型的一般情况

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-05-16 DOI:10.1051/mmnp/2024008
Djilali salih
{"title":"具有不同扩散率的延迟时空宿主-病原体感染模型的一般情况","authors":"Djilali salih","doi":"10.1051/mmnp/2024008","DOIUrl":null,"url":null,"abstract":"We propose a general model to investigate the effect of the distinct dispersal coefficient {for the} infected and susceptible hosts on the pathogen dynamics. The mathematical challenge lies in the fact that the investigated model is partially degenerate and the solution map is not compact. The spatial heterogeneity of the model parameters and the distinct diffusion coefficients induce infection in the low-risk regions. In fact, as infection dispersal increases, the reproduction of the pathogen particles decreases. The dynamics of the investigated model is governed by the value of the basic reproduction number $R_0$. {If $R_0\\leq1$, then the} pathogen particles extinct, and for $R_0>1$ the pathogen particles persist, and we guarantees of the existence of at least one positive steady state. The asymptotic profile of the positive steady state is shown in the case when one or both diffusion coefficients for the host tends to zero or infinity.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":"59 13","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Generalities on a delayed spatiotemporal host-pathogen infection model with distinct dispersal rates\",\"authors\":\"Djilali salih\",\"doi\":\"10.1051/mmnp/2024008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We propose a general model to investigate the effect of the distinct dispersal coefficient {for the} infected and susceptible hosts on the pathogen dynamics. The mathematical challenge lies in the fact that the investigated model is partially degenerate and the solution map is not compact. The spatial heterogeneity of the model parameters and the distinct diffusion coefficients induce infection in the low-risk regions. In fact, as infection dispersal increases, the reproduction of the pathogen particles decreases. The dynamics of the investigated model is governed by the value of the basic reproduction number $R_0$. {If $R_0\\\\leq1$, then the} pathogen particles extinct, and for $R_0>1$ the pathogen particles persist, and we guarantees of the existence of at least one positive steady state. The asymptotic profile of the positive steady state is shown in the case when one or both diffusion coefficients for the host tends to zero or infinity.\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":\"59 13\",\"pages\":\"\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2024-05-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://doi.org/10.1051/mmnp/2024008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1051/mmnp/2024008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0

摘要

我们提出了一个通用模型来研究{感染宿主和易感宿主的}不同扩散系数对病原体动态的影响。数学上的挑战在于所研究的模型是部分退化的,解图并不紧凑。模型参数的空间异质性和不同的扩散系数会诱发低风险区域的感染。事实上,随着感染扩散的增加,病原体粒子的繁殖会减少。所研究模型的动态受基本繁殖数 $R_0$ 值的支配。{如果 $R_0\leq1$,则}病原体粒子灭绝;如果 $R_0>1$,则病原体粒子持续存在,我们保证至少存在一个正稳态。当宿主的一个或两个扩散系数趋于零或无穷大时,正稳态的渐近曲线就会显示出来。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Generalities on a delayed spatiotemporal host-pathogen infection model with distinct dispersal rates
We propose a general model to investigate the effect of the distinct dispersal coefficient {for the} infected and susceptible hosts on the pathogen dynamics. The mathematical challenge lies in the fact that the investigated model is partially degenerate and the solution map is not compact. The spatial heterogeneity of the model parameters and the distinct diffusion coefficients induce infection in the low-risk regions. In fact, as infection dispersal increases, the reproduction of the pathogen particles decreases. The dynamics of the investigated model is governed by the value of the basic reproduction number $R_0$. {If $R_0\leq1$, then the} pathogen particles extinct, and for $R_0>1$ the pathogen particles persist, and we guarantees of the existence of at least one positive steady state. The asymptotic profile of the positive steady state is shown in the case when one or both diffusion coefficients for the host tends to zero or infinity.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
期刊最新文献
Correction to "Three in One: In Vitro and In Vivo Evaluation of Anticancer Activity of a Theranostic Agent that Combines Magnetic Resonance Imaging, Optical Bioimaging, and Photodynamic Therapy Capabilities". Trastuzumab Conjugation Enhances HER2-Positive Cell Association and Intratumoral Retention of Magnetite Nanoparticles for Magnetic Hyperthermia. Cell Membrane Targeting via Spacer Length-Engineered Amphiphilic DNA Frameworks. Facile Microemulsion Preparation of Paclitaxel-Loaded Silk Fibroin Nanoparticles Using Polyethylene Glycol for Glioblastoma Therapy. Silk Sericin Functionalized with Carboxy Drugs for Dermocosmetic Applications.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1