登革热在儿童患者中的临床表现和处理方法

Abdul Haseeb, Sharanabasappa, Hareesh
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摘要

目的:登革热对全球健康构成重大挑战,尤其影响流行地区的儿童。登革热的临床表现多种多样,从轻微到严重,如登革出血热(DHF)和登革热休克综合征(DSS),这使儿童登革热的诊断和管理变得更加复杂。鉴于登革热给全球带来的巨大负担,了解其临床细微差别至关重要。研究方法这项前瞻性横断面研究在雅舒达超级专科医院儿科进行,旨在调查 6 个月至 16 岁儿童登革热患者的临床、实验室和影像学特征。统计分析采用 SPSS 19.0 版进行。结果在 100 名登记的儿童患者中,高烧(100%)、头痛(75%)、肌痛(70%)、皮疹(65%)和出血性表现(40%)是主要的临床特征。实验室检查结果显示,60%的病例血小板减少,30%的病例肝酶升高。相关性分析确定了特定症状与诊断结果之间的关联,有助于识别 DSS 等严重病例。结论该研究强调了小儿登革热的多种临床表现,强调了警惕性临床评估和实验室检测对及时诊断和管理的重要性。这些见解对于优化患者护理和治疗效果至关重要,尤其是在登革热流行地区。
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CLINICAL PRESENTATION AND MANAGEMENT OF DENGUE IN PEDIATRIC PATIENTS
Objective: Dengue fever poses a significant challenge to global health, particularly affecting children in endemic regions. The diverse clinical presentations, ranging from mild to severe forms such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), complicate its diagnosis and management in pediatric populations. Understanding the clinical nuances is crucial, given the substantial global burden of dengue. Methods: This prospective cross-sectional study conducted at the Department of Pediatrics, Yashoda Super Specialty Hospital, aimed to investigate the clinical, laboratory, and radiological features of dengue fever in pediatric patients aged 6 mo to 16 y. Data collection involved demographic details, clinical presentations, laboratory findings, and treatment administered. Statistical analysis was performed using SPSS version 19.0. Results: Among the 100 enrolled pediatric patients, high fever (100%), headache (75%), myalgia (70%), rash (65%), and hemorrhagic manifestations (40%) were prevalent clinical features. Laboratory findings revealed thrombocytopenia in 60% of cases and elevated liver enzymes in 30%. Correlation analyses identified associations between specific symptoms and diagnostic findings, aiding in the recognition of severe cases such as DSS. Conclusion: The study highlights the diverse clinical spectrum of pediatric dengue, emphasizing the importance of vigilant clinical assessment and laboratory testing for timely diagnosis and management. These insights are essential for optimizing patient care and outcomes, particularly in endemic regions.
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