接种 COVID-19 疫苗对巴比伦省 SARS-CoV-2 再感染的保护作用

F. A. Alzubaidi, E. Oubaid, Zahraa I. J. Shubber, Hussam W. Al-Humadi, Rafal J. Al-Saigh
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摘要

世界各地都有导致2019年冠状病毒病(COVID-19)的严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)再感染的记录。目前,有关 COVID-19 疫苗对 SARS-CoV-2 再感染的保护作用的证据还很有限。这项病例对照研究旨在评估巴比伦省接种 COVID-19 疫苗与 SARS-CoV-2 再感染之间的关系;研究使用了电子问卷。受感染的患者有 115 人(年龄≥18 岁),并经 PCR 阳性和/或 CT 扫描确认,他们在再感染日期前已接种或未接种第二剂(辉瑞、阿斯利康或国药集团)疫苗,并与 300 名对照组参与者进行了比较。研究结果表明,未接种疫苗者再次感染的几率是接种了全部疫苗者的4.5倍,且不区分疫苗生产商。结论表明,全面接种COVID-19疫苗可以大大降低再感染的可能性,提高整体保护能力,并将未来感染的风险降至最低。
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Protective effect of COVID-19 vaccination against a SARS-CoV-2 reinfection in the Babil Province
Reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has been documented all over the world. Currently, limited evidence exists concerning the protec¬tion afforded by the COVID-19 vaccination against reinfection with SARS-CoV-2. This case-control study was per¬formed in order to assess the association between COVID-19 vaccination and SARS-CoV-2 reinfection in the Babil Province; the study used an electronic questionnaire. The infected patients were 115 (aged ≥18 years) and were confirmed by a positive PCR and/or a CT scan, they were either fully vaccinated or not with a second dose of a (Pfizer, AstraZeneca, or Sinopharm) vaccine before the reinfection date, and they were compared with 300 control partici¬pants. The study’s findings revealed that the unvaccinated individuals had 4.5 times the odds of reinfection compared to those who were fully vaccinated, without preference for the manufacturer of the vaccine. The conclusion suggests that getting fully vaccinated against COVID-19 can significantly reduce the likelihood of reinfection, can enhance overall protection, and can minimize the risk of future infections.
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