{"title":"作为药物载体的无机聚合物:机遇与挑战","authors":"B. Divband","doi":"10.61873/ccdw2092","DOIUrl":null,"url":null,"abstract":"Innovative methods and significant developments in designing new synthetic inorganic materials have been used to overcome limitations of current drug delivery systems. Inorganic polymers are widely used in the field of biomedicine, imaging, tissue engineering and drug delivery because of their bioactivity, biocompatibility, and stability. A few of the more well-known wholly inorganic polymers are portland cement, silicon dioxide, polyanionic glasses (including titania- and aluminosilicate glasses), poly(sulphur nitride), polycrystalline diamond, graphite, poly(sulphur nitride), and alumi¬num-silicate materials. Inorganic polymers, especially those possessing significant porosity, are good potential candi¬dates for the delivery of several drugs (anticancer, antibiotics, and anti-inflammatories), providing advantages such as encapsulation, controlled delivery, and improved targeting of drugs. Choosing a suitable drug carrier with a selec¬tive targeting potential also seems to be a very promising way for improving stability as well as selectivity. Despite all the advances, developing homogeneous inorganic polymers with narrow molecular weight distributions is a multidis¬ciplinary challenge. The current keynote speech provides a review of the opportunities and challenges of using inor¬ganic polymers as drug carriers.","PeriodicalId":515365,"journal":{"name":"Review of Clinical Pharmacology and Pharmacokinetics - International Edition","volume":"273 29‐32","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Inorganic polymers as drug carriers: opportunities and challenges\",\"authors\":\"B. Divband\",\"doi\":\"10.61873/ccdw2092\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Innovative methods and significant developments in designing new synthetic inorganic materials have been used to overcome limitations of current drug delivery systems. Inorganic polymers are widely used in the field of biomedicine, imaging, tissue engineering and drug delivery because of their bioactivity, biocompatibility, and stability. A few of the more well-known wholly inorganic polymers are portland cement, silicon dioxide, polyanionic glasses (including titania- and aluminosilicate glasses), poly(sulphur nitride), polycrystalline diamond, graphite, poly(sulphur nitride), and alumi¬num-silicate materials. Inorganic polymers, especially those possessing significant porosity, are good potential candi¬dates for the delivery of several drugs (anticancer, antibiotics, and anti-inflammatories), providing advantages such as encapsulation, controlled delivery, and improved targeting of drugs. Choosing a suitable drug carrier with a selec¬tive targeting potential also seems to be a very promising way for improving stability as well as selectivity. Despite all the advances, developing homogeneous inorganic polymers with narrow molecular weight distributions is a multidis¬ciplinary challenge. The current keynote speech provides a review of the opportunities and challenges of using inor¬ganic polymers as drug carriers.\",\"PeriodicalId\":515365,\"journal\":{\"name\":\"Review of Clinical Pharmacology and Pharmacokinetics - International Edition\",\"volume\":\"273 29‐32\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Review of Clinical Pharmacology and Pharmacokinetics - International Edition\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.61873/ccdw2092\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Review of Clinical Pharmacology and Pharmacokinetics - International Edition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.61873/ccdw2092","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inorganic polymers as drug carriers: opportunities and challenges
Innovative methods and significant developments in designing new synthetic inorganic materials have been used to overcome limitations of current drug delivery systems. Inorganic polymers are widely used in the field of biomedicine, imaging, tissue engineering and drug delivery because of their bioactivity, biocompatibility, and stability. A few of the more well-known wholly inorganic polymers are portland cement, silicon dioxide, polyanionic glasses (including titania- and aluminosilicate glasses), poly(sulphur nitride), polycrystalline diamond, graphite, poly(sulphur nitride), and alumi¬num-silicate materials. Inorganic polymers, especially those possessing significant porosity, are good potential candi¬dates for the delivery of several drugs (anticancer, antibiotics, and anti-inflammatories), providing advantages such as encapsulation, controlled delivery, and improved targeting of drugs. Choosing a suitable drug carrier with a selec¬tive targeting potential also seems to be a very promising way for improving stability as well as selectivity. Despite all the advances, developing homogeneous inorganic polymers with narrow molecular weight distributions is a multidis¬ciplinary challenge. The current keynote speech provides a review of the opportunities and challenges of using inor¬ganic polymers as drug carriers.