印度尼西亚男性雄激素性脱发患者的三镜特征与疾病严重程度的关系

Q2 Medicine International Journal of Trichology Pub Date : 2023-07-01 Epub Date: 2024-04-05 DOI:10.4103/ijt.ijt_31_22
Lili Legiawati, Lis Surachmiati Suseno, Irma Bernadette S Sitohang, Shannaz Nadia Yusharyahya, Athaya Ardelia, Kanya Paramastri
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引用次数: 0

摘要

导言:雄激素性脱发(AGA)是一种进行性末端毛发脱落,其分布模式与雄激素有关。对头发和头皮进行皮肤镜检查,即毛囊镜检查,是诊断脱发及其他头发和头皮疾病的一种非侵入性方法:本研究旨在报告根据汉密尔顿-诺伍德量表得出的男性 AGA 严重程度与毛发镜检查发现的临床特征之间的相关性:研究对象包括在印度尼西亚一家三级医疗机构皮肤科门诊就诊的 40 名患者,年龄在 25-58 岁之间。通过病史采集、体格检查和毛囊镜检查确定临床诊断。根据汉密尔顿-诺伍德标准,患者被分为两组:早期和晚期。毛发镜检查的参数包括黄点、白点、毛周征、绒毛、毛发直径多样性、单发毛囊和空毛囊。采用卡方检验(Chi-square test)和费雪精确检验(Fisher's exact test)分析各组之间的统计学意义:所有参与者都有头发直径多样性、单发毛囊和空毛囊(100%)。没有人出现黄点。白点和单发毛囊分别出现在 32 例(80%)和 30 例(75%)中。在晚期组中,这些特征更为普遍。25名参与者(62.50%)发现了毛周征象,这种征象在早期组中更为常见。疾病严重程度与三镜检查特征之间无明显关联:结论:最常见的毛囊镜检查结果依次是毛发直径多样性、绒毛和空毛囊,其次是白点、单发毛囊和毛周征象。脱发严重程度与毛囊镜检查参数之间没有明显关联。应进行更多参与者(包括对照组)的研究,以获得更显著的结果。
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Trichoscopy Features of Indonesian Males with Androgenetic Alopecia in Association with Disease Severity.

Introduction: Androgenetic alopecia (AGA) is a progressive loss of terminal hairs in a specific pattern distribution related to androgen. The dermoscopy of hair and scalp, known as trichoscopy, is a noninvasive method for diagnosing alopecia and other hair and scalp disorders.

Objective: This study aims to report the correlation between the severity of males with AGA based on Hamilton-Norwood's scale with the clinical characteristics found in trichoscopy.

Materials and methods: This study included 40 patients aged 25-58 years who visited the dermatology outpatient clinic in a tertiary health facility in Indonesia. Clinical diagnosis was determined through history taking, physical examination, and trichoscopy. Based on Hamilton-Norwood's criteria, patients were divided into two groups: early and late stage. Parameters examined in trichoscopy include yellow dots, white dots, peripilar sign, vellus hair, hair diameter diversity, single-hair follicles, and empty follicles. The Chi-square test and Fisher's exact test were used to analyze the statistical significance between the groups.

Results: All participants presented with hair diameter diversity, vellus hair, and empty follicles (100%). None of the study participants had yellow dots. White dots and single-hair follicles were seen in 32 (80%) and 30 cases (75%), respectively. In the late-stage group, these features were more prevalent. Peripilar sign was found in 25 participants (62.50%), and it was more common in the early-stage group. No significant association was found between disease severity and trichoscopy features.

Conclusion: The most common trichoscopy findings in particular order were hair diameter diversity, vellus hair, and empty follicles, followed by white dots, single-hair follicles, and peripilar signs. No significant association between alopecia severity and trichoscopy parameters was observed. Studies with a larger number of participants, including a control group, should be conducted to yield more significant results.

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来源期刊
CiteScore
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0.00%
发文量
38
期刊最新文献
A Cross-sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes. A Study of Serum Ferritin and Thyroid-Stimulating Hormone Levels in Male Patients with Androgenetic Alopecia. Alopecia Areata with Renal Dysgenesis. Graham-Little-Piccardi-Lassueur Syndrome with Mucosal Involvement: A Rare Case. Mucinous Lupus Alopecia with Papulonodular Mucinosis as a Sole Cutaneous Manifestation of Systemic Lupus Erythematosus.
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