膳食中添加植酸酶和刺激素可降低肉鸡在铁丝网斜坡挑战模型中的死亡率和跛行率。

IF 2.5 2区 农林科学 Q1 VETERINARY SCIENCES Avian Pathology Pub Date : 2024-06-26 DOI:10.1080/03079457.2024.2359592
Elizabeth S Greene, Alison Ramser, Robert Wideman, Mike Bedford, Sami Dridi
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引用次数: 0

摘要

摘要 细菌性软骨坏死伴骨髓炎(BCO)导致的跛行是由于免疫抑制或肠胃功能衰退而渗入血液循环的机会性细菌感染软弱的骨骼。一种缓解策略是在日粮中添加一些产品,以支持肉鸡的整体健壮性和骨骼健康。为了测试植酸酶和刺激素补充剂缓解跛足的能力,肉鸡在垫料地板或铁丝斜坡上饲养 56 天以诱发 BCO,并饲喂 6 种日粮中的一种:阳性对照(PC);阴性对照(NC、钙和磷缺乏);PC 加刺激素;PC 加刺激素和植酸酶;NC 加植酸酶;NC 加刺激素和植酸酶。刺激素的添加量为 100 克/吨,植酸酶的添加量为 3000 FTU/公斤。在第 56 天或因跛足被淘汰时,对鸟类的 BCO 进行评分。无论采用哪种处理方法,斜坡上的全因死亡率均高于窝内死亡率。铁丝斜坡对跛行有明显诱导作用,在 NC 日粮中发生率最高。重要的是,在NC日粮中添加抗生素和植酸酶后,跛行率降低了50%。NC组60%的股骨BCO评分≥1分,而添加刺激性生物素和植酸酶的组为30%-37%,这表明这些添加剂可影响家禽跛足的发生/发展。血浆和骨肌醇水平之间不存在相关性;但是,无论日粮如何,铁丝地板都会降低骨肌醇水平。此外,斜坡上的血液 pH 值更高,循环中的 PCO2、HCO3、BE、TCO2、K、血细胞比容和血红蛋白均低于垫料上的。
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Dietary inclusion of phytase and stimbiotic decreases mortality and lameness in a wire ramp challenge model in broilers.

Research highlights: Wire ramp model reproducibly induced lameness/BCO in broilers.Treatments did not affect growth, but phytase with stimbiotic significantly reduced BCO.Phytase increased circulating inositol, and wire flooring decreased bone inositol.

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来源期刊
Avian Pathology
Avian Pathology 农林科学-兽医学
CiteScore
4.50
自引率
10.70%
发文量
68
审稿时长
1 months
期刊介绍: Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.
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