上肢假肢用天然橡胶乳胶化妆手套:制备及物理化学、机械和生物学特性分析

Danielle Restelatto , Jordana Bortoluz , Paula Sartori , Nayrim B. Guerra , Cristiani C.P. Cid , Robinson C.D. Cruz , Noel M. Gately , Declan M. Devine , Marcelo Giovanela , Mariana Roesch-Ely , Janaina S. Crespo
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引用次数: 0

摘要

上肢截肢往往是创伤事件造成的,通常与车祸或涉及工业机械的事故有关。假肢技术的发展对于为截肢者提供身体上的帮助和心理上的支持至关重要。在这种情况下,可以利用化妆手套来增强与生物手相似的视觉特征,从而提高个人和社会的舒适度。在这项工作中,我们在天然橡胶乳胶(NRL)的基础上开发了具有抗菌特性的配方,并在其中加入了一种由氧化锌和纳米银颗粒组成的添加剂,用于制造上肢假肢用化妆手套。通过显微技术研究了添加剂的分散效率。此外,还进行了拉伸和撕裂强度测试、邵氏 A 硬度测量、膨胀指数、疏水性和细菌生长抑制,以确定所开发材料的适用性和适应性,以便将其融入患者的日常活动中。此外,还评估并验证了用于浸泡成型生产化妆手套的加工参数,突出了生产技术与材料特性之间的重要关系。总之,研究结果表明,将添加剂与高交联密度的 NRL 结合使用,可有效改善材料的机械性能,使拉伸强度高达 20.7 兆帕,撕裂强度约为 40 kN m-1。此外,根据抗菌测试,手套对金黄色葡萄球菌具有抑菌作用,对大肠杆菌具有杀菌作用。总之,数据集表明,制造的化妆手套可用于覆盖上肢假肢。此外,通过使用适当的配方和 NRL 加工技术,它还强调了化妆手套制造业的巨大潜力。
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Cosmetic gloves from natural rubber latex for upper limb prostheses: Preparation and physicochemical, mechanical and biological characterization

Upper limb amputations are frequently the result of traumatic events, often associated with car accidents or incidents involving industrial machinery. The development of prosthetic technologies is essential to provide physical assistance to amputees and offer psychological support. In such circumstances, cosmetic gloves can be utilized to improve personal and social comfort by enhancing visual characteristics similar to those of a biological hand. In this work, we developed formulations based on natural rubber latex (NRL) with antibacterial properties by the incorporation of an additive consisting of zinc oxide coated with silver nanoparticles to manufacture cosmetic gloves designed for upper limb prostheses. The dispersion efficiency of the additive was investigated by microscopic techniques. Tensile and tear strength tests, Shore A hardness measurements, swelling indices, hydrophobicity and inhibition of bacterial growth were also conducted to ascertain the suitability and adaptability of the developed material for integration into the daily activities of patients. Moreover, processing parameters for the immersion molding production of cosmetic gloves were assessed and validated, highlighting the crucial relationship between manufacturing techniques and material properties. Overall, the results indicated that the combination of the additive with a high crosslinking density of NRL effectively improved the material mechanical properties, resulting in a tensile strength of up to 20.7 MPa and a tear strength of approximately 40 kN m−1. In addition, and according to the antibacterial tests, the gloves exhibited bacteriostatic effects against Staphylococcus aureus and bactericidal effects against Escherichia coli. As a conclusion, the dataset indicates that the manufactured cosmetic gloves can be used to covering upper limb prostheses. Additionally, it underscores the considerable potential for the cosmetic glove manufacturing industry through the use of appropriate formulations and processing techniques for NRL.

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Biomedical engineering advances
Biomedical engineering advances Bioengineering, Biomedical Engineering
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审稿时长
59 days
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