药物再利用概述。

3区 生物学 Q2 Biochemistry, Genetics and Molecular Biology Progress in Molecular Biology and Translational Science Pub Date : 2024-01-01 Epub Date: 2024-04-06 DOI:10.1016/bs.pmbts.2024.03.026
Khushal Khambhati, Abdulrahman H Alessa, Vijai Singh
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引用次数: 0

摘要

新型药物的鉴定和实施不仅费时费力,而且在进入市场方面也面临巨大挑战。目前,美国食品和药物管理局(USFDA)批准的数以千计的药物许可证已经过期,这些药物可以重新用于治疗其他疾病。药物再利用是一种替代解决方案,可以减少药物开发及其用于治疗疾病的时间、成本和步骤。本章重点介绍药物研发和药物再利用的步骤。本章还包括治疗细菌、真菌和病毒性疾病的再利用药物。发掘已有药物的潜力并将其重新用于其他疾病,可以加速药物发现并帮助管理疾病爆发。
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An overview to drug repurposing.

Identification and implementation of novel drug are not only time consuming and expensive but also it poses huge challenge to reach into the market. Currently, thousands of USFDA approved drugs licence are being expired that can be repurposed for treating other diseases. Drug repurposing is an alternative solution to reduce time, cost and steps for development of drugs and their applications for treating disease. The current chapter emphases to brief the steps involved in drug discovery and drug repurposing. The chapter also includes repurposed drugs for treating bacterial, fungal and viral diseases. Unlocking the potential of already existed drug and repurposing them for other diseases that could accelerate drug discovery and aid in managing outbreaks.

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来源期刊
CiteScore
5.00
自引率
0.00%
发文量
110
审稿时长
4-8 weeks
期刊介绍: Progress in Molecular Biology and Translational Science (PMBTS) provides in-depth reviews on topics of exceptional scientific importance. If today you read an Article or Letter in Nature or a Research Article or Report in Science reporting findings of exceptional importance, you likely will find comprehensive coverage of that research area in a future PMBTS volume.
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