意大利各地区 COVID-19 患者重症监护病房床位占用率的多波建模和短期预测

IF 5.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-05-23 DOI:10.1051/mmnp/2024012
Frederico José Ribeiro Pelogia, Henrique Mohallem Paiva, Roberson Saraiva Polli
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引用次数: 0

摘要

贡献:本研究通过采用代表多重流行病学浪潮的现象学模型,深入探讨了 COVID-19 的动态变化。其目的是为卫生部门和医院管理者提供决策支持,尤其是在优化重症监护室(ICU)床位管理和实施有效遏制措施方面。背景:鉴于重症监护室环境错综复杂,利用数学模型预测占用率非常有益,并可能降低与 COVID-19 相关的死亡率。本研究的重点是意大利各地区在多次流行病学浪潮中重症监护患者人数的变化情况。研究方法:我们的方法包括应用低复杂度的现象学模型和高效的优化程序。我们利用意大利五个人口大区的重症监护室入住率数据来证明该模型在描述历史数据和提供两周间隔预测方面的有效性。研究结果:通过分析 ICU 入住率数据,研究证实了所提模型的有效性。该模型成功地拟合了历史数据并提供了准确的预测,在所有地区的整体拟合和预测中,平均相对均方根误差分别为 0.51%和 0.93%。除了眼前的情况,该模型的低复杂性和高效优化使其适用于不同地区和疾病,支持未来流行病的跟踪和遏制。
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Multi-wave modelling and short-term prediction of ICU bed occupancy by patients with COVID-19 in regions of Italy
Contribution: This study provides insights into COVID-19 dynamics by employing a phenomenological model representing multiple epidemiological waves. It aims to support decision-making for health authorities and hospital administrators, particularly in optimizing Intensive Care Unit (ICU) bed management and implementing effective containment measures. Background: Given the intricate complexity of ICU environments, utilizing a mathematical model to anticipate occupancy is highly beneficial and might mitigate mortality rates associated with COVID-19. The study focuses on the evolution of intensive care patient numbers across multiple epidemiological waves in Italian regions. Methodology: Our methodology involves the application of a low-complexity phenomenological model with an efficient optimization procedure. ICU occupancy data from five populous Italian regions are utilized to demonstrate the model’s efficacy on describing historical data and providing forecasts for two-week intervals. Findings: Drawing from the analyzed ICU occupancy data, the study establishes the effectiveness of the proposed model. It successfully fits historical data and offers accurate forecasts, achieving an average relative RMSE of 0.51% for the whole fit and 0.93% for the predictions, across all regions. Beyond the immediate context, the model low complexity and efficient optimization make it suitable to diverse regions and diseases, supporting the tracking and containment of future epidemics.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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