基于就业的应急措施对药物滥用障碍患者接受治疗、保持治疗和长期戒断的影响:系统回顾

N. M. Harry, Ibrahim Folorunsho, Nnenna Okafor, Oluwatosin Arubuolawe, Gibson Anugwom
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摘要

背景和目的:药物使用障碍(SUD)仍然是一个重大的公共卫生问题,也是发病率和死亡率的一个重要原因。本研究的目的是探讨并确定就业应急方案(EBC)对 SUD 患者接受治疗、坚持治疗率以及治疗后戒断率的影响。研究方法使用检索词((药物使用障碍)和(失业))或(治疗性工作场所)对 PubMed 和 Google Scholar 进行检索。或(治疗工作场所))),搜索 2012 年至 2022 年间发表的随机对照试验(RCT),报告对象为 18 至 65 岁使用阿片类药物、可卡因或酒精的参与者。结果:有七项随机对照试验符合标准并实现了研究目标,共有 389 名参与者。在这七项研究中,有三项有 203 名参与者的研究发现,EBC 对治疗注册率有积极影响,注册率分别为 100%、92% 和 100%。三篇有 172 人参与的文章发现,与对照组相比,EBC 参与者的治疗依从率和治疗保持率更高。与对照组相比,EBC 组中纳曲酮阳性尿液的比例更高(72% 对 21%,P 值为 0.01),74%(EBC)对 26%(对照组)的参与者完成了治疗。四篇有 238 名参与者的文章发现,EBC 使戒断率提高了 50%以上,是未接受 EBC 治疗的对照组的两倍。结论:EBC 能够有效提高 SUD 治疗的注册率、治疗的依从性和治疗后的戒断率,但是,其效果可能取决于获得奖励的多少。
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The Effect of Employment-Based Contingency on Treatment Enrollment, Retention, and Long-Term Abstinence among Individuals with Substance use Disorder: A Systematic Review
Background and Objective: Substance use disorders (SUD) remain a major public health concern and represent a significant cause of morbidity and mortality. Our goal in this study is to explore and determine the effect(s) of employment-based contingency (EBC) on enrolling SUD individuals into treatment, the rate of treatment adherence, and the rate of post-treatment abstinence. Methods: PubMed and Google Scholar search was conducted using the search terms ((substance use disorder) AND (unemployment)) OR (therapeutic workplace)), for randomized controlled trials (RCT) published between 2012 and 2022, reporting on participants between ages 18 and 65 years who use opioids, cocaine or alcohol. Results: Seven RCT which met the criteria and addressed the study objectives had a total of 389 participants. Three RCT of the seven with 203 participants found EBC to positively impact the rate of enrollment to treatment with 100%, 92%, and 100% enrollment rates in the respective studies. Three articles with 172 participants found a higher rate of treatment adherence and retention to treatment among EBC participants compared to the control group. There was more naltrexone-positive urine in the EBC group compared to control (72% vs. 21%, with a p-value of .01), and 74% (EBC) vs 26% (control) participants completed treatment. Four articles with 238 participants found that EBC improved the rate of abstinence by over 50%, which is double the rate among the control group without EBC. Conclusion: EBC is effective in improving SUD treatment enrollment, treatment adherence, and post-treatment abstinence, however, the efficacy may be dependent on how much is earned as an incentive.
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