体育锻炼对阿尔茨海默病发病的影响

Joanna Paśnik, Gabriela Sendecka, Natalia Kistela, Izabela Hądzlik, Marcin Durowicz, Jan Piotrowski
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引用次数: 0

摘要

阿尔茨海默病是最常见的痴呆症,也是现代社会因人口老龄化而面临的一项挑战。研究人员正竭尽全力了解其发病机制,并寻找治疗和预防这种疾病的有效方法。本文旨在介绍体育锻炼对阿尔茨海默病发病的影响。大量研究证实,经常锻炼对延缓大脑衰老和减轻患者的神经精神症状有积极作用。在肌肉锻炼过程中会产生鸢尾素,它在神经元的形成过程中发挥着重要作用,并具有抗炎作用。这篇综述还探讨了保持肠道微生物群适当组成的问题,因为肠道微生物群失衡会促进神经元炎症过程和认知功能障碍。此外,还关注了训练强度和运动对大脑血流的影响等问题。所有这些因素在预防和减缓神经退化方面都发挥着重要作用。
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Impact of physical activity on the development of Alzheimer's disease
Alzheimer's disease is the most common form of dementia and is a challenge for the modern world due to the due to aging populations. Researchers are trying their best to understand the mechanisms of onset and find effective ways to treat and prevent this disease. The purpose of the following paper is to present the impact of physical activity in the development of Alzheimer's disease. Numerous studies confirm that regular workouts have a positive reflection in the form of slowing the aging of the brain and alleviation of neuropsychiatric symptoms in affected individuals. During muscle work irisin is produced, which plays an important role in the formation of neurons and exhibits an anti-inflammatory effects. This review also looks at the aspect of maintaining proper composition of the gut microbiota, whose imbalance can promote the process of neuronal inflammation and cognitive dysfunction. Attention is also given to issues of training intensity and the effect of of exercise on blood flow in the brain. All of these elements play an important role in preventing and slowing down neurodegeneration.
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