慢性阻塞性肺病患者动脉血气模式的描述性研究

Mohan J, Basavaraju T J, Darshan G R, S. B. L.
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摘要

背景:慢性阻塞性肺病是全球慢性病发病和死亡的主要原因之一。它是全球第四大死因(1)。慢性阻塞性肺病的慢性气ow 限是由小气道疾病(阻塞性支气管炎)和实质损害(肺气肿)混合造成的,两者的相对作用因人而异。研究的目的和目标:研究慢性阻塞性肺疾病表型中动脉血气的变化。研究方法:本描述性研究针对 2021 年 8 月至 2021 年 10 月期间入住班加罗尔维多利亚医院的慢性阻塞性肺疾病患者。动脉血气分析被用作 110 例慢性阻塞性肺病患者的诊断测试。解释与结论:ABG 采样是气体交换成功与否、氧合作用的更精确测量,也是通气成功与否的唯一可靠测定,可通过二氧化碳含量重新。它还能提供病人病程中某一特定c 点酸碱平衡的宝贵信息,在慢性阻塞性肺病的管理中发挥重要作用。在慢性阻塞性肺病缓解期和加重期接受常规治疗的患者,其病程较慢。据统计,在缓解期接受正规治疗的患者,pH 值和 PaO2 的降低以及 PaCO2 的升高明显较。ABG 分析适用于急性加重期、辅助通气期间和决定预后。ABG 分析应成为患者管理不可或缺的一部分。
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A DESCRIPTIVE STUDY OF ARTERIAL BLOOD GAS PATTERNS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Background: COPD is one of the major causes of chronic morbidity and mortality worldwide. It is the fourth leading cause of death in the world(1). Chronic airow limitation of COPD is caused by a mixture of small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), the relative contributions of which vary from person to person. Aim and Objective of the study: To Study the changes of Arterial blood gases in COPD phenotypes. Methods: This Descriptive study was carried out on the patients with chronic obstructive pulmonary disease who were admitted to Victoria hospital, Bangalore from AUGUST 2021 to OCTOBER 2021. Arterial blood gas analysis was used as a diagnostic test in 110 cases of Chronic Obstructive Pulmonary Disease. Interpretation and Conclusion: ABG sampling constitutes a more precise measure of successful gas exchange, oxygenation and happens to be only reliable determination of ventilation success as reected by CO2 content . It also provides valuable information on the acid base balance at a specic point in the course of a patient's illness and plays an important role in the management of Chronic Obstructive Pulmonary Disease. Patients regularly treated in phases of Remission and Exacerbations of COPD the course of illness is slower. Decrease of pH and PaO2 and increase of PaCO2 is statistically signicantly smaller in those received regular treatment in phases of remissions. ABG analysis is indicated in acute exacerbations, during assisted ventilation and to decide prognosis. It should become an integral part of patient management.
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