兔霉菌毒素概述

IF 1.2 3区 农林科学 Q3 VETERINARY SCIENCES Journal of Veterinary Diagnostic Investigation Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI:10.1177/10406387241255945
Theodora K Tsouloufi
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引用次数: 0

摘要

霉菌毒素中毒通常是对大型动物的影响,但也会影响伴侣动物。由于人们对兔子的兴趣日益浓厚,而且兔子很容易被用作实验室模型,越来越多已发表的实验研究讨论了各种霉菌毒素对这一物种的影响。然而,现有的证据是零散和不统一的,据我所知,最近还没有整理成综述。虽然兔子的霉菌毒素中毒通常是亚临床症状,但临床症状可能包括体重减轻、厌食、胃肠功能紊乱、生长迟缓、生殖异常和易感染。死前诊断通常依赖于全面的临床病史、临床症状评估和相关的实验室检查结果,并通过测定饲料或目标器官中的霉菌毒素浓度来确认是否接触了霉菌毒素。我的综述侧重于对兔子最重要的霉菌毒素(包括伏马菌毒素、赭曲霉毒素、黄曲霉毒素、单端孢霉烯和玉米赤霉烯酮)的临床病理学和组织病理学影响。本综述全面概述了霉菌毒素对家兔的影响,是兽医从业人员、诊断人员和研究人员的一站式参考资料。
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An overview of mycotoxicoses in rabbits.

Mycotoxicoses are usually a consideration in large animal species but can affect companion animals as well. Due to increasing interest and the ease of using rabbits as laboratory models, a growing number of published experimental studies discuss the effects of various mycotoxins on this species. However, the available evidence is fragmented and heterogeneous, and has not recently been collated in a review, to my knowledge. Although mycotoxicoses in rabbits are typically subclinical, clinical signs can include weight loss, anorexia, gastrointestinal disorders, stunted growth, reproductive abnormalities, and susceptibility to infections. An antemortem diagnosis typically relies on a comprehensive clinical history, and assessment of clinical signs and relevant laboratory findings, with confirmation of exposure achieved through the measurement of mycotoxin concentrations in feed or target organs. My review focuses on the clinicopathologic and histopathologic effects of the mycotoxins most important in rabbits, including fumonisins, ochratoxins, aflatoxins, trichothecenes, and zearalenone. This review offers a thorough overview of the effects of mycotoxins in rabbits, serving as a one-stop resource for veterinary practitioners, diagnosticians, and researchers.

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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
127
审稿时长
6-16 weeks
期刊介绍: The Journal of Veterinary Diagnostic Investigation (J Vet Diagn Invest) is an international peer-reviewed journal published bimonthly in English by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). JVDI is devoted to all aspects of veterinary laboratory diagnostic science including the major disciplines of anatomic pathology, bacteriology/mycology, clinical pathology, epidemiology, immunology, laboratory information management, molecular biology, parasitology, public health, toxicology, and virology.
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