添加层制造的生物聚合物的冲击和扭转行为:骨科应用的进步。

IF 3.2 4区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Biopolymers Pub Date : 2024-05-29 DOI:10.1002/bip.23600
Shrutika Sharma, Deepa Mudgal, Vishal Gupta
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引用次数: 0

摘要

尺骨远端锁定骨板(DLBPs)通常用于治疗尺骨远端骨折。然而,市售的金属骨板会产生应力屏蔽,并且缺乏耐腐蚀性。聚乳酸(PLA)因其与人体组织的生物相容性和生物可吸收性而成为备受青睐的生物聚合物。增材分层制造(ALM)的使用越来越受到人们的关注,它可以制造出具有复杂结构的定制植入物,以满足患者的自主需求。基于 ALM 的聚乳酸骨板必须具有较高的抗冲击和抗扭转能力,因此有必要调整打印工艺参数。本研究重点考察了关键印刷参数对 DLBPs 的冲击强度和扭矩承受能力的影响。实验结果和显微图像显示,填充密度(IF)和壁厚的增加可增强层在冲击和扭转载荷下抵抗裂纹扩展的能力。相反,层高和印刷速度的增加会导致层在冲击和扭转测试中分层和早期断裂。IF 对提高 DLBPs 的抗冲击强度和抗扭转能力做出了重大贡献,分别提高了 70.53% 和 80.65%。这项研究凸显了 ALM 技术在为生物医学应用开发具有足够机械强度的 DLBPs 方面的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Impact and torsional behavior of additive layer-manufactured biopolymer: An advancement for orthopedic applications

Distal ulna locking bone plates (DLBPs) are commonly employed in the treatment of distal ulna fractures. However, commercially available metallic bone plates experience stress shielding and lack corrosion resistance. Poly lactic acid (PLA) is highly favored biopolymer due to its biocompatible and bioabsorbable nature with human tissues. The use of additive layer manufacturing (ALM) is gaining attention for creating customized implants with intricate structures tailored to patient autonomy. ALM-based PLA bone plates must provide high resistance against impact and torsional forces, necessitating the adjustment of printing process parameters. This study focuses on examining the influence of key printing parameters, on the impact strength and torque-withstanding capability of DLBPs. Experimental results, along with microscopic images, reveal that an increase in infill density (IF) and wall thickness imparts strong resistance to layers against crack propagation under impact and torsional loads. On the contrary, an increase in layer height and printing speed leads to delamination and early fracture of layers during impact and torsional testing. IF significantly contributes to improving the impact strength and torque-withstanding capability of DLBPs by 70.53% and 80.65%, respectively. The study highlights the potential of the ALM technique in developing DLBPs with sufficient mechanical strength for biomedical applications.

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来源期刊
Biopolymers
Biopolymers 生物-生化与分子生物学
CiteScore
5.30
自引率
0.00%
发文量
48
审稿时长
3 months
期刊介绍: Founded in 1963, Biopolymers publishes strictly peer-reviewed papers examining naturally occurring and synthetic biological macromolecules. By including experimental and theoretical studies on the fundamental behaviour as well as applications of biopolymers, the journal serves the interdisciplinary biochemical, biophysical, biomaterials and biomedical research communities.
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