印度北部一家三级医疗中心采用 Cephid CT/NG Xpert 快速 PCR 检测沙眼衣原体和淋病奈瑟菌的效果。

IF 1.4 4区医学 Q4 IMMUNOLOGY Indian Journal of Medical Microbiology Pub Date : 2024-06-08 DOI:10.1016/j.ijmmb.2024.100639

Sunil Sethi , Rajendra Gudisa , Nandita Sharma , Priya Sreenivasan , Parakriti Gupta , Hemant Chaudary , Tarun Narang , Rashmi Bagga

{"title":"印度北部一家三级医疗中心采用 Cephid CT/NG Xpert 快速 PCR 检测沙眼衣原体和淋病奈瑟菌的效果。","authors":"Sunil Sethi , Rajendra Gudisa , Nandita Sharma , Priya Sreenivasan , Parakriti Gupta , Hemant Chaudary , Tarun Narang , Rashmi Bagga","doi":"10.1016/j.ijmmb.2024.100639","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p><em>Chlamydia trachomatis</em> (CT) and <em>Neisseria gonorrhoeae</em> (NG) are prevalent causes of sexually transmitted infections (STIs) globally, leading to substantial morbidity and transmission risks.</p></div><div><h3>Methods</h3><p>This study evaluates the diagnostic efficacy of Xpert CT/NG compared to conventional PCR and culture methods in 121 patients at a tertiary care centre in North India.</p></div><div><h3>Results</h3><p>Xpert CT/NG demonstrated high sensitivity (85.8%) and specificity (96.3%) outperforming conventional PCR. Xpert CT/NG's rapidity and accuracy underscore its utility in timely diagnosis and control of STIs.</p></div><div><h3>Conclusion</h3><p>As sexually transmitted infections pose a serious health concern implementation of such rapid diagnostic methods/point of care testing methods are to be implemented for early diagnosis.</p></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"50 ","pages":"Article 100639"},"PeriodicalIF":1.4000,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Performance of Cephid CT/NG Xpert rapid PCR test for detection of Chlamydia trachomatis and Neisseria gonorrhoeae at a tertiary care centre in North India\",\"authors\":\"Sunil Sethi , Rajendra Gudisa , Nandita Sharma , Priya Sreenivasan , Parakriti Gupta , Hemant Chaudary , Tarun Narang , Rashmi Bagga\",\"doi\":\"10.1016/j.ijmmb.2024.100639\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p><em>Chlamydia trachomatis</em> (CT) and <em>Neisseria gonorrhoeae</em> (NG) are prevalent causes of sexually transmitted infections (STIs) globally, leading to substantial morbidity and transmission risks.</p></div><div><h3>Methods</h3><p>This study evaluates the diagnostic efficacy of Xpert CT/NG compared to conventional PCR and culture methods in 121 patients at a tertiary care centre in North India.</p></div><div><h3>Results</h3><p>Xpert CT/NG demonstrated high sensitivity (85.8%) and specificity (96.3%) outperforming conventional PCR. Xpert CT/NG's rapidity and accuracy underscore its utility in timely diagnosis and control of STIs.</p></div><div><h3>Conclusion</h3><p>As sexually transmitted infections pose a serious health concern implementation of such rapid diagnostic methods/point of care testing methods are to be implemented for early diagnosis.</p></div>\",\"PeriodicalId\":13284,\"journal\":{\"name\":\"Indian Journal of Medical Microbiology\",\"volume\":\"50 \",\"pages\":\"Article 100639\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-06-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Medical Microbiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0255085724001142\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Microbiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0255085724001142","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

导言：沙眼衣原体（CT）和淋病奈瑟菌（NG）是全球性传播感染（STI）的主要病原体，会导致严重的发病率和传播风险：本研究评估了 Xpert CT/NG 与传统 PCR 和培养方法相比在印度北部一家三级医疗中心 121 名患者中的诊断效果：Xpert CT/NG 的灵敏度（85.8%）和特异性（96.3%）均高于传统 PCR。Xpert CT/NG 的快速性和准确性突显了它在及时诊断和控制性传播感染方面的作用：结论：性传播感染是一个严重的健康问题，因此应采用此类快速诊断方法/护理点检测方法进行早期诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Performance of Cephid CT/NG Xpert rapid PCR test for detection of Chlamydia trachomatis and Neisseria gonorrhoeae at a tertiary care centre in North India

Introduction

Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are prevalent causes of sexually transmitted infections (STIs) globally, leading to substantial morbidity and transmission risks.

Methods

This study evaluates the diagnostic efficacy of Xpert CT/NG compared to conventional PCR and culture methods in 121 patients at a tertiary care centre in North India.

Results

Xpert CT/NG demonstrated high sensitivity (85.8%) and specificity (96.3%) outperforming conventional PCR. Xpert CT/NG's rapidity and accuracy underscore its utility in timely diagnosis and control of STIs.

Conclusion

As sexually transmitted infections pose a serious health concern implementation of such rapid diagnostic methods/point of care testing methods are to be implemented for early diagnosis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.