慢消化淀粉和抗性淀粉对葡萄糖稳态和胰岛素抵抗的影响

IF 3 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI:10.1097/MCO.0000000000001044
Maëliss Chisbert, Anne-Laure Castell, Sophie Vinoy, Julie-Anne Nazare
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引用次数: 0

摘要

综述目的:本综述将总结最近的研究,评估慢消化淀粉(SDS)和抗性淀粉(RS)对健康、糖尿病前期或 2 型糖尿病成人葡萄糖代谢的影响:摘要:碳水化合物(CHO),尤其是淀粉在预防和控制代谢性疾病(如 2 型糖尿病(T2D))方面发挥着重要作用。这在很大程度上取决于摄入淀粉类产品的质量和消化率(速度和程度),而不是数量。对 SDS 的研究较少,但它对减少健康和胰岛素抵抗受试者的血糖波动有好处,并有可能改善 2 型糖尿病患者的血糖控制。至于 RS,研究结果似乎令人鼓舞,但仍不尽相同,这取决于 RS 的性质及其对微生物群的调节作用。还需要进一步的研究来证实目前的结果,并调查 SDS 和 RS 对长期葡萄糖稳态的潜在互补有益作用,以预防心脏代谢疾病。
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The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance.

Purpose of review: This review will summarize recent studies assessing the effect of slowly digestible starch (SDS) and resistant starch (RS) on glucose metabolism in healthy, prediabetic or type 2 diabetic adults.

Recent findings: Currently, a particular interest in starch and its digestibility has arisen, with data showing a positive effect of SDS and RS on the glucose homeostasis of healthy, at-risk, prediabetic and type 2 diabetic patients but research is ongoing.

Summary: Carbohydrates (CHO) and especially starch play a major role in the prevention and management of metabolic diseases such as type 2 diabetes (T2D). This largely depends on the quality and the digestibility (rate and extent) of the ingested starchy products, beyond their quantity. SDS have been poorly studied but display a beneficial effect on reducing glucose excursions in healthy and insulin-resistant subjects and a relevant potential to improve glucose control in type 2 diabetic individuals. As for RS, the results appear to be encouraging but remain heterogeneous, depending the nature of the RS and its role on microbiota modulation. Further studies are needed to confirm the present results and investigate the potential complementary beneficial effects of SDS and RS on long-term glucose homeostasis to prevent cardiometabolic diseases.

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来源期刊
CiteScore
5.30
自引率
6.50%
发文量
116
审稿时长
6-12 weeks
期刊介绍: A high impact review journal which boasts an international readership, Current Opinion in Clinical Nutrition and Metabolic Care offers a broad-based perspective on the most recent and exciting developments within the field of clinical nutrition and metabolic care. Published bimonthly, each issue features insightful editorials and high quality invited reviews covering two or three key disciplines which include protein, amino acid metabolism and therapy, lipid metabolism and therapy, nutrition and the intensive care unit and carbohydrates. Each discipline introduces world renowned guest editors to ensure the journal is at the forefront of knowledge development and delivers balanced, expert assessments of advances from the previous year.
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