以纳米多孔金薄膜为基底,利用低温原子探针断层扫描技术分析液体。

IF 2.9 4区 工程技术 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Microscopy and Microanalysis Pub Date : 2025-02-03 DOI:10.1093/mam/ozae041
Eric V Woods, Aparna Saksena, Ayman A El-Zoka, Leigh T Stephenson, Tim M Schwarz, Mahander P Singh, Leonardo S Aota, Se-Ho Kim, Jochen Schneider, Baptiste Gault
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引用次数: 0

摘要

目前正在开发低温原子探针断层成像技术(cryo-APT),以便对冷冻液体进行纳米级成分分析。然而,如何获得既能固定液体又能为液体界面提供足够强度的现成基底仍是一个问题。在此,我们建议使用 1-2 微米厚的金银二元合金薄膜,将其溅射到平面硅上,无需附加层即可获得足够的附着力。通过化学脱合金,我们成功地制造出了一种具有开孔结构的纳米多孔基底,并通过聚焦离子束系统中的提升装置将其安装在硅柱微阵列上,从而实现了液体的低温固定。我们展示了经过低温锐化、真空低温转移以及对纳米多孔膜顶部和内部的纯水进行分析后获得的低温-APT 结果。我们证明,这种新型基底具有促进冷冻液体低温-APT 的必要特性,而且贵金属含量相对较低。从制备薄膜到成功将液体固定在多孔网络中,再到低温-APT,这一完整的工作流程代表了一种改进的冷冻液体分析方法。
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Nanoporous Gold Thin Films as Substrates to Analyze Liquids by Cryo-atom Probe Tomography.

Cryogenic atom probe tomography (cryo-APT) is being developed to enable nanoscale compositional analyses of frozen liquids. Yet, the availability of readily available substrates that allow for the fixation of liquids while providing sufficient strength to their interface is still an issue. Here, we propose the use of 1-2-µm-thick binary alloy film of gold-silver sputtered onto flat silicon, with sufficient adhesion without an additional layer. Through chemical dealloying, we successfully fabricate a nanoporous substrate, with an open-pore structure, which is mounted on a microarray of Si posts by lift-out in the focused-ion beam system, allowing for cryogenic fixation of liquids. We present cryo-APT results obtained after cryogenic sharpening, vacuum cryo-transfer, and analysis of pure water on the top and inside the nanoporous film. We demonstrate that this new substrate has the requisite characteristics for facilitating cryo-APT of frozen liquids, with a relatively lower volume of precious metals. This complete workflow represents an improved approach for frozen liquid analysis, from preparation of the films to the successful fixation of the liquid in the porous network, to cryo-APT.

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来源期刊
Microscopy and Microanalysis
Microscopy and Microanalysis 工程技术-材料科学:综合
CiteScore
1.10
自引率
10.70%
发文量
1391
审稿时长
6 months
期刊介绍: Microscopy and Microanalysis publishes original research papers in the fields of microscopy, imaging, and compositional analysis. This distinguished international forum is intended for microscopists in both biology and materials science. The journal provides significant articles that describe new and existing techniques and instrumentation, as well as the applications of these to the imaging and analysis of microstructure. Microscopy and Microanalysis also includes review articles, letters to the editor, and book reviews.
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