与工作有关的噪声暴露与认知障碍之间的关系:中国的一项横断面研究

IF 3.4 3区 医学 Q2 NEUROSCIENCES Journal of Alzheimer's Disease Pub Date : 2024-06-01 DOI:10.3233/jad-240061
Lei Huang, Jingxuan Ma, Fugui Jiang, Shushan Zhang, Y. Lan, Yang Zhang
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引用次数: 0

摘要

背景:噪音暴露和认知障碍风险是当前主要的公共健康问题。研究目的本研究旨在从职业流行病学的角度分析噪声暴露与认知功能早期受损之间的关系,并为老龄化背景下痴呆症的长期预防和治疗提供证据。研究方法本研究于 2021 年 5 月至 8 月在中国进行。自变量为有害因素类型、噪声暴露持续时间、感知噪声强度和累积噪声暴露(CNE)。因变量为认知功能,采用迷你精神状态检查(MMSE)和蒙特利尔认知评估(MoCA)进行测量。采用多元线性回归和逻辑回归分析噪声暴露与认知功能之间的关系,并建立效应曲线。研究结果使用 MMSE 和 MoCA 的认知功能障碍检出率分别为 1.1% 和 36.2%。在 90-140 dB.time 的 CNE 值范围内,预测的 MMSE 和 MoCA 分数呈下降趋势。CNE 每增加一个单位,认知功能得分就分别降低 0.025 (0.037, 0.013) 分和 0.020 (0.037, 0.003) 分。结论从职业流行病学的角度来看,这些研究结果揭示了长期暴露于噪声环境与早期认知障碍之间的潜在联系。
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Relationship Between Work-Related Noise Exposure and Cognitive Impairment: A Cross-Sectional Study in China
Background: Noise exposure and the risk of cognitive impairment are currently major public health issues. Objective: This study aimed to analyze the relationship between noise exposure and early impairment of cognitive function from the perspective of occupational epidemiology and to provide evidence for the long-term prevention and treatment of dementia in the context of aging. Methods: This study was conducted in China between May and August 2021. The independent variables were the type of hazardous factors, duration of noise exposure, perceived noise intensity, and cumulative noise exposure (CNE). The dependent variable was cognitive function, which was measured using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Multiple linear and logistic regression were used to analyze the relationship between noise exposure and cognitive function and to establish an effect curve. Results: The detection rates of cognitive dysfunction using the MMSE and MoCA were 1.1% and 36.2%, respectively. The predicted MMSE and MoCA scores showed a downward trend within the CNE value ranging from 90–140 dB.time. Each unit increase in CNE decreased cognitive function scores by 0.025 (0.037, 0.013) and 0.020 (0.037, 0.003) points,respectively. Conclusions: From the perspective of occupational epidemiology, these findings reveal a potential link between long-term noise exposure and early cognitive impairment.
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来源期刊
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease 医学-神经科学
CiteScore
6.40
自引率
7.50%
发文量
1327
审稿时长
2 months
期刊介绍: The Journal of Alzheimer''s Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer''s disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer''s disease.
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