认识天然产品的药效学成分

IF 3 3区 医学 Q2 PHARMACOLOGY & PHARMACY Saudi Pharmaceutical Journal Pub Date : 2024-06-02 DOI:10.1016/j.jsps.2024.102124
Tao Wang , Zhong-Yu Fu , Yan-Juan Li , Lei Zi , Cheng-Zhu Song , Yu-Xuan Tao , Mei Zhang , Wen Gu , Jie Yu , Xing-Xin Yang
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引用次数: 0

摘要

天然产物(NPs)在干预各种疾病方面发挥着不可替代的作用,一直被认为是药物开发的重要来源。最近,许多具有潜在临床应用价值的新药效化合物都是从天然产物中提取出来的。这些化合物包括小分子、多糖、多肽、蛋白质、自组装纳米颗粒和细胞外囊泡。本综述总结了在纳米粒子中发现的各种活性物质。对 NPs 中活性物质的研究可促进新药开发,并有助于深入了解 NPs 的作用机制,从而有利于预防和治疗人类疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recognition on pharmacodynamic ingredients of natural products

Natural products (NPs) play an irreplaceable role in the intervention of various diseases and have been considered a critical source of drug development. Many new pharmacodynamic compounds with potential clinical applications have recently been derived from NPs. These compounds range from small molecules to polysaccharides, polypeptides, proteins, self-assembled nanoparticles, and extracellular vesicles. This review summarizes various active substances found in NPs. The investigation of active substances in NPs can potentiate new drug development and promote the in-depth comprehension of the mechanism of action of NPs that can be beneficial in the prevention and treatment of human diseases.

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来源期刊
Saudi Pharmaceutical Journal
Saudi Pharmaceutical Journal PHARMACOLOGY & PHARMACY-
CiteScore
6.10
自引率
2.40%
发文量
194
审稿时长
67 days
期刊介绍: The Saudi Pharmaceutical Journal (SPJ) is the official journal of the Saudi Pharmaceutical Society (SPS) publishing high quality clinically oriented submissions which encompass the various disciplines of pharmaceutical sciences and related subjects. SPJ publishes 8 issues per year by the Saudi Pharmaceutical Society, with the cooperation of the College of Pharmacy, King Saud University.
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