印度儿童先天性眼部及其附件异常。

IF 1.9 Bioinformation Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI:10.6026/973206300200323
Preethi Chava, Chaitra Mc, Raveena J, Amulya Padmini
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引用次数: 0

摘要

对 0-12 岁儿童眼部疾病的先天性病因进行分析很有意义。因此,这项研究于 2021 年 1 月至 2023 年 12 月在印度卡纳塔克邦科拉市塔玛卡的斯里德瓦拉杰乌尔斯医学院附属 RL Jalappa 医院和研究中心进行,为期两年。在 56 名患者中,57% 为男性,43% 为女性。31名母亲(55%)的年龄在20-30岁之间,24名母亲(43%)的年龄在31-40岁之间,1名母亲(2%)的年龄在41-50岁之间。在 56 名患者中,14 人(25%)有阳性家族史。其中 34 人(61%)有近亲结婚。34人中有14人(41%)的父母为二等血亲(兄弟/姐妹/祖父母/外祖父母),20人(59%)为三等血亲(姑姑/舅舅/侄女/外甥/曾祖父母/曾外祖父母)。31例(55%)患者为双侧受累。鼻泪管异常最常见(32%),其次是先天性内斜视(14%)。关于近亲结婚风险和其他风险因素(如产妇年龄、感染、孕期用药、疫苗接种等)的教育、宣传和咨询必须成为医疗机构的常规做法。这将大大降低发病率并预防失明。
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Congenital ocular and its adnexal anomalies among Indian pediatric age groups.

An analysis of the congenital etiologies of ocular morbidity in children of age 0-12 years is of interest. Hence, this study was conducted over a period of 2 years from Jan 2021- Dec 2023 at RL Jalappa Hospital and Research center that is attached to Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India. Out of 56 patients, 57% were male and 43% were female children. 31 (55%) of mothers belonged to age group between 20-30 years and 24 (43%) between 31-40 years and 1(2%) between 41-50 years. Out of 56 patients, 14 (25%) of them had positive family history. 34 (61%) of them had consanguious marriage. 14 parents (41%) out of 34 are married to second degree consanguinity (brother/sister/grandparent/grandchild) and 20 (59%) belonged to third degree consanguinity (aunt/uncle/niece/nephew/great-grandparent/great-grandchild). Bilateral involvement was seen in 31 (55%). Nasolacrimal duct anomalies were found to be the most common (32%) followed by congenital esotropia (14%). Education, awareness, counseling about risks of consanguinity and other risk factors such as maternal age, infections, medications during pregnancy, vaccination must be a routine practice in healthcare set up. This can significantly reduce morbidity and prevent blindness.

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Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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