改良放疗舱中来自中子污染的剂量当量考虑:蒙特卡洛研究。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Biomedical Physics & Engineering Express Pub Date : 2024-06-20 DOI:10.1088/2057-1976/ad567c
Pegah Saadatmand, Seied Rabi Mahdavi, Nahid Chegeni, Amir Hossein Karimi
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引用次数: 0

摘要

包含金属片的层压屏障可为空间受限的放射治疗中心提供有效保护。本研究旨在评估在使用 18 MV 光子束进行模拟盆腔放疗时,由不同成分的多层屏障保护的较小拱顶内的光中子污染情况。研究人员使用 18 MV LINAC(瓦里安 2100 C/D)和医用内部辐射剂量(MIRD)模型进行蒙特卡洛模拟,以评估盆腔放疗过程中不同金属板和硼化聚乙烯(BPE)组合的重建拱顶内的光中子污染情况。研究结果表明,与混凝土相比,使用铅板和钢板的重建拱顶迷宫沿线的环境中子剂量 H_n^* (10) 分别增加了 3.27 倍和 2.91 倍。使用金属板后,治疗室外的 H_n^* (10) 增加了,但即使工作量为 1000Gy/周,它仍未超过 LINAC 掩体附近非控制区 20 μSv/week 的允许限值。患者器官中的中子当量剂量介于 0.22 至 0.96 mSv/Gy 之间。各种层状屏障成分在器官的中子当量剂量、致命癌症风险、二次辐射诱发癌症风险和癌症死亡率方面没有明显区别。此外,在拱顶壁重建中使用金属板可使光中子诱发癌症的风险变化保持在 6% 以下,而致命癌症和癌症死亡率的风险变化则低于 11%。虽然层状隔热箱的金属部分会提高中子剂量,但增加 BPE 板可减少对有效剂量增加和二次恶性肿瘤风险的担忧。
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Dose equivalent consideration from neutron contamination in modified radiotherapy vault: a Monte Carlo study.

Laminated barriers incorporating metal sheets provide effective protection for space-restricted radiotherapy centers. This study aimed to assess photoneutron contamination in smaller vaults protected by different compositions of multilayer barriers during simulated pelvic radiotherapy with 18 MV photon beams. Monte Carlo Simulations of 18 MV LINAC (Varian 2100 C/D) and Medical Internal Radiation Dose (MIRD) phantom were used to assess photoneutron contamination within reconstructed vaults incorporating different combinations of metal sheet and borated polyethylene (BPE) during pelvic radiotherapy. The findings highlight a 3.27 and 2.91 times increase in ambient neutron doseHn*(10) along the maze of reconstructed vaults that use lead and steel sheets, respectively, compared to concrete. TheHn*(10) outside the treatment room increased after incorporating a metal sheet, but it remained within the permissible limit of 20μSv/week for uncontrolled areas adjacent to the LINAC bunker, even with a workload of 1000Gy/week. Neutron equivalent doses in the patient's organs ranged from 0.22 to 0.96 mSv Gy-1. There is no notable distinction in the organ's neutron equivalent dose, fatal cancer risk, secondary radiation-induced cancer risk, and cancer mortality for various laminated barrier compositions. Furthermore, the use of metal sheets for vault wall reconstruction keeps the variation in cancer risk induced by photoneutrons below 6%, while risks of fatal cancer and cancer mortality vary less than 11%. While the metal portion of the laminated barrier raises the neutron dose, the addition of a BPE plate reduces concerns of increased effective dose and secondary malignancy risk.

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来源期刊
Biomedical Physics & Engineering Express
Biomedical Physics & Engineering Express RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.80
自引率
0.00%
发文量
153
期刊介绍: BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.
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