[预防子痫前期及其并发症]。

Revue medicale de Liege Pub Date : 2024-06-01
Marine Allard, Stéphanie Grosch, François Jouret, Véronique Masson, Tracy Surinder, Catherine Masset
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引用次数: 0

摘要

子痫前期是一种妊娠期特有的疾病,其特点是妊娠 20 周后出现妊娠高血压,并伴有蛋白尿或器官功能障碍。全世界有 2% 至 8% 的妊娠会并发先兆子痫,在发达国家,它是导致孕产妇和胎儿死亡的主要原因。唯一明确的治疗方法仍然是终止妊娠和胎盘娩出。应及时评估孕产妇和胎儿的状况,根据孕龄寻找严重程度标准和适当的治疗方法。孕妇最担心的是即将发生的子痫或胎盘早剥,而胎儿的并发症则来自胎盘功能不全和过早终止妊娠的风险。目前唯一有效的子痫前期预防方法是每天给高危患者服用 160 毫克的阿司匹林。子痫前期现已被认为是心血管、肾脏和神经系统疾病的高危因素,因此应将其视为筛查和预防的机会。
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[Prevention of preeclampsia and its complications].

Preeclampsia is a pregnancy-specific condition characterized by gestational hypertension associated with proteinuria or organ dysfunction after 20 weeks of gestation. It complicates 2 to 8 % of pregnancies worldwide and represents the leading cause of maternal and fetal mortality in developed countries. The only definitive treatment remains termination of pregnancy and delivery of the placenta. Prompt assessment of maternal and fetal status should be held in search of severity criteria and adequate management of this condition according to gestational age. Foremost concerns for pregnant patients are impending eclampsia or placental abruption, while fetal complications arise from placental insufficiency and risks associated with premature pregnancy termination. The sole efficient prophylaxis of preeclampsia in current state of evidence is aspirin at a dosage of 160 mg per day in high risk patients. Preeclampsia is now recognized as a high-risk factor for cardiovascular, renal, and neurological diseases and should therefore be considered as an opportunity for screening and prevention.

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