新型荧光探针揭示了 ME/CFS 成纤维细胞中的脂滴动力学(传感器研究进展 6/2024)

Siyang Ding, Oana Sanislav, Daniel Missailidis, Claire Yvonne Allan, Tze Cin Owyong, Ming-Yu Wu, Sijie Chen, Paul Robert Fisher, Sarah Jane Annesley, Yuning Hong
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引用次数: 0

摘要

脂滴成像在第 2300178 号文章中,Yuning Hong 及其合作者介绍了一种新开发的细胞脂滴成像剂。这种高性能的荧光染料能够量化活细胞中脂滴的动态变化,与健康对照组相比,它能显示出 ME/CFS 患者成纤维细胞中更大但更少的脂滴,这表明它在疾病研究和诊断中具有潜在的应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A Novel Fluorogenic Probe Reveals Lipid Droplet Dynamics in ME/CFS Fibroblasts (Adv. Sensor Res. 6/2024)

Lipid Droplet Imaging

In article 2300178, Yuning Hong and co-workers present a newly developed imaging agent for cellular lipid droplets. This high-performance fluorescent dye is capable to quantify lipid droplet dynamics in live cells and reveals larger but fewer lipid droplets in fibroblasts from ME/CFS patients compared to the healthy controls, suggesting their potential application in disease study and diagnosis.

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