内源性阿片类药物及其受体的基础科学。

Q3 Neuroscience Advances in neurobiology Pub Date : 2024-01-01 DOI:10.1007/978-3-031-45493-6_2

Simona Tache, Patrick L Kerr, Cristian Sirbu

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摘要

内源性阿片类药物的功能包括启动对生存至关重要的行为，以及对快速变化的环境条件做出反应。内源性阿片类物质系统（EOS）是一个遍布全身的相互关联的系统网络。内源性阿片系统受体包括β-内啡肽、脑啡肽、达因啡肽和内吗啡肽，这些受体支撑着内源性阿片系统在各个生物系统中发挥不同的功能。本章简明而全面地概述了 EOS 的结构、EOS 受体及其与其他生物系统的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Foundational Science of Endogenous Opioids and Their Receptors.

The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.

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