患者对带状银屑病发病率和负担的看法:美国成人银屑病患者全国调查结果》。

IF 3.5 3区 医学 Q1 DERMATOLOGY Dermatology and Therapy Pub Date : 2024-07-01 Epub Date: 2024-06-14 DOI:10.1007/s13555-024-01190-4
Teri Greiling, Melodie Young, Melissa S Seal, Robert C Higham, April Armstrong
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引用次数: 0

摘要

简介:Harris Poll 代表 Arcutis Biotherapeutics 在美国进行了一项调查,以了解使用处方外用疗法治疗银屑病的患者的观点和负担。本手稿介绍了三叉神经间银屑病患者子集的调查结果:调查于 2021 年 10 月 21 日至 11 月 24 日在线进行,对象是 507 名年龄在 18 岁以上、经医疗机构诊断为银屑病且目前正在使用处方外用药治疗的美国成年人。三叉神经间银屑病患者是指症状出现在腋窝、腹股沟、乳房下、腹部皱褶或臀部之间的斑块状银屑病患者:在 507 名受访者中,有 320 人(64%)曾报告在三叉神经间部位出现过症状,其中以臀部之间为典型(31%)。大多数三叉神经间银屑病患者表示,这让他们感到尴尬(80%)、焦虑(79%)或抑郁(69%)。此外,这些患者中有 45% 的人表示三叉神经间银屑病对性焦虑或性困难造成了负面影响。腹股沟受累的患者中有 16% 的人称生活质量受到了 "非常严重的负面影响",而腹股沟未受累的患者中只有 6%;女性患者中有 15% 的人称生活质量受到了 "非常严重的负面影响",而男性患者中只有 6%。三叉神经间银屑病患者表示,与三叉神经间银屑病相关的瘙痒(61%)、脱屑(53%)、发红(49%)和皮肤皲裂(46%)对生活质量的负面影响最大。这些患者中的大多数(86%)表示,如果能采用单一治疗方案治疗身体的所有患病部位,他们会更加坚持治疗:结论:银屑病在病程中累及三叉神经间区域的情况很常见,会对这些患者的生活质量,尤其是情感健康和性健康造成负面影响。
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Patient Perspectives on the Prevalence and Burden of Intertriginous Psoriasis: Results from a National Survey of Adults with Psoriasis in the United States.

Introduction: A survey was conducted by The Harris Poll on behalf of Arcutis Biotherapeutics in the USA to understand perspectives and burden of patients with psoriasis using prescription topical treatments for their disease. This manuscript presents results from the subset of patients with intertriginous psoriasis.

Methods: The survey was conducted online October 21-November 24, 2021, among 507 US adults aged 18+ years with psoriasis diagnosed by a healthcare provider and currently using prescription topical treatment. Participants with intertriginous psoriasis were patients with plaque psoriasis reporting symptoms in the armpit, groin, under breast, stomach fold, or between the buttocks.

Results: Of the 507 respondents, 320 (64%) reported symptoms in intertriginous areas at some point, typically between the buttocks (31%). Most patients with intertriginous psoriasis reported it made them feel embarrassed (80%), anxious (79%), or depressed (69%). In addition, 45% of these patients reported intertriginous psoriasis caused a negative impact on sexual anxiety or distress. Quality of life impact was reported as "very strong negative impact" in 16% of patients with groin involvement vs. 6% in patients with no groin involvement and 15% in women vs. 6% in men. Patients with intertriginous psoriasis reported that itch (61%), scaling (53%), redness (49%), and skin cracking (46%) related to intertriginous psoriasis had the greatest negative impact on quality of life. Most (86%) of these patients said they would be more adherent if a single treatment option could be used to treat all affected areas of their body.

Conclusion: Psoriasis involvement in intertriginous areas over the course of disease is common and has a negative impact on these patients' quality of life, particularly emotional well-being and sexual health.

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来源期刊
Dermatology and Therapy
Dermatology and Therapy Medicine-Dermatology
CiteScore
6.00
自引率
8.80%
发文量
187
审稿时长
6 weeks
期刊介绍: Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.
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