JN.1 和正在进行的战斗:解读 COVID-19 新变种的特征。

IF 4.9 4区 医学 Q1 PARASITOLOGY Pathogens and Global Health Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI:10.1080/20477724.2024.2369378
Reza Eshraghi, Ashkan Bahrami, Motahare Karimi Houyeh, Maryam Nasr Azadani
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摘要

在 COVID-19 出现的第四年,一种新的 COVID-19 变异株 JN.1 出现并在全球范围内传播,并成为多个地区的优势菌株。它的尖峰蛋白有一些特殊的突变,使其具有更高的传播性。就这一问题的意义而言,了解 JN.1 的临床和免疫学特征对于在全球范围内加强卫生策略和疫苗接种工作至关重要,其最终目标是加强我们对这一流行病的集体应对。在本研究中,我们探讨了有关 JN.1 特征和突变的最新发现,以及它对绕过免疫系统的影响。我们证明了在医疗保健框架内进行持续监控和战略调整的重要性,以及废水采样对快速识别新出现的 SARS-CoV-2 变异体的重要意义。
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JN.1 and the ongoing battle: unpacking the characteristics of a new dominant COVID-19 variant.

In the fourth year of the COVID-19 occurrence, a new COVID-19 variant, JN.1, has emerged and spread globally and become the dominant strain in several regions. It has some specific mutations in its spike proteins, empowering it with higher transmissibility. Regarding the significance of the issue, understanding the clinical and immunological traits of JN.1 is critical for enhancing health strategies and vaccination efforts globally, with the ultimate goal of bolstering our collective response to the pandemic. In this study, we take a look at the latest findings of JN.1 characteristics and mutations as well as its consequences on bypassing immune system. We demonstrate the importance of continual surveillance and strategic adaptation within healthcare frameworks along with the significance of wastewater sampling for the rapid identification of emerging SARS-CoV-2 variants.

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来源期刊
Pathogens and Global Health
Pathogens and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY
CiteScore
6.00
自引率
0.00%
发文量
60
审稿时长
6-12 weeks
期刊介绍: Pathogens and Global Health is a journal of infectious disease and public health that focuses on the translation of molecular, immunological, genomics and epidemiological knowledge into control measures for global health threat. The journal publishes original innovative research papers, reviews articles and interviews policy makers and opinion leaders on health subjects of international relevance. It provides a forum for scientific, ethical and political discussion of new innovative solutions for controlling and eradicating infectious diseases, with particular emphasis on those diseases affecting the poorest regions of the world.
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