{"title":"慢性肾病患儿依他西嗪促心律失常作用的罕见变异发展（临床病例）","authors":"O. V. Kotomina, V. V. Pogodin, Yu. L. Pazgaleva","doi":"10.18705/2782-3806-2024-4-2-180-188","DOIUrl":null,"url":null,"abstract":"This article describes a rare clinical case of the development of severe ventricular tachycardia while taking etacizine in a 3-year-8-month-old patient with chronic kidney disease. A clinical case demonstrates the pharmacodynamics and pharmacokinetics of class 1C antiarrhythmic drugs in pediatric patients with kidney pathology.","PeriodicalId":499018,"journal":{"name":"Russian Journal for Personalized Medicine","volume":"31 25","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A rare variant of the development of the proarrhythmogenic effect of etacizine in a child with chronic kidney disease (clinical case)\",\"authors\":\"O. V. Kotomina, V. V. Pogodin, Yu. L. Pazgaleva\",\"doi\":\"10.18705/2782-3806-2024-4-2-180-188\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article describes a rare clinical case of the development of severe ventricular tachycardia while taking etacizine in a 3-year-8-month-old patient with chronic kidney disease. A clinical case demonstrates the pharmacodynamics and pharmacokinetics of class 1C antiarrhythmic drugs in pediatric patients with kidney pathology.\",\"PeriodicalId\":499018,\"journal\":{\"name\":\"Russian Journal for Personalized Medicine\",\"volume\":\"31 25\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal for Personalized Medicine\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.18705/2782-3806-2024-4-2-180-188\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal for Personalized Medicine","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.18705/2782-3806-2024-4-2-180-188","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A rare variant of the development of the proarrhythmogenic effect of etacizine in a child with chronic kidney disease (clinical case)
This article describes a rare clinical case of the development of severe ventricular tachycardia while taking etacizine in a 3-year-8-month-old patient with chronic kidney disease. A clinical case demonstrates the pharmacodynamics and pharmacokinetics of class 1C antiarrhythmic drugs in pediatric patients with kidney pathology.
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