静脉曲张后患者肌钙蛋白和红细胞分布宽度水平与死亡率之间的关系

M. Doganci, Güler Eraslan Doğanay
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引用次数: 0

摘要

导言:TR值表示肌钙蛋白和红细胞分布宽度(RDW)的同时增加,是Covid-19疾病中常见的心肌损伤标志物,有关TR值的研究很少。本研究旨在显示肌钙蛋白、RDW 和 TR 值与 Covid-19 后死亡率和预后因素的关系。方法:研究纳入了 2021 年 4 月至 2022 年 3 月期间入住成人三级 Covid ICU 的 204 名确诊为 Covid-19 的患者。对患者的人口统计学数据、合并症、治疗、重症监护和住院时间以及实验室指标进行了评估。根据本医院的参考范围,RDW值超过16%和肌钙蛋白值超过15ng/L被定义为高值。同时肌钙蛋白值超过 15ng/L 和 RDW 值超过 16% 的患者被视为高 TR。结果:在研究中,当检查出院时/出院前的数值时发现,肌钙蛋白和 TR 水平高的患者插管率更高,机械通气时间更长。与 RDW 和 TR 值较低的患者相比,RDW 和 TR 值较高的患者出院前/出院时的血小板、血红蛋白和血细胞比容值较低。结论我们的研究发现,肌钙蛋白和 TR 值升高的患者插管率更高,机械通气时间更长。我们认为,本诊所对 TR 值高和饱和度降低的患者采用早期插管的做法可降低死亡率。
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Relationship between Troponin and Red Cell Distribution Width Levels and Mortality in Post-Covid Patients
Introduction: There are very few studies on the TR value, which expresses the simultaneous increase in Troponin and Red Cell Distribution Width (RDW), which are markers of myocardial damage commonly seen in Covid-19 disease. This study aims to show the relationship of troponin, RDW and TR values with mortality and prognostic factors post-Covid-19. Methods: 204 patients diagnosed with Covid-19 who were admitted to the adult tertiary Covid ICU between April,2021 and March,2022 were included in the study. Demographic data, comorbidities, treatments, length of stay in intensive care and hospital, and laboratory parameters were evaluated. According to our hospital's reference ranges, RDW value over 16% and troponin value over 15ng/L were defined as high value. Patients with both troponin value over 15ng/L and RDW value over 16% were considered to have high TR. Results: In the study, when the values checked at the time of discharge/before discharge were examined, it was seen that the intubation rate was higher and the duration of mechanical ventilation was longer in patients with high troponin and TR levels. In patients with high RDW and TR values, platelet, hemoglobin and hematocrit values were lower before discharge/discharge compared to those with low RDW and TR values. Conclusion: In our study, it was found that the intubation rate was higher and mechanical ventilation durations were longer in patients with elevated troponin and TR. We are of the opinion that early intubation practices applied in our clinic for patients with high TR and desaturation are reduced mortality.
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