青少年的社交焦虑症状及其与自杀意念和抑郁症状的关系:前瞻性研究

JCPP advances Pub Date : 2024-06-10 DOI:10.1002/jcv2.12249
Kenny Chiu, A. Stringaris, E. Leigh
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摘要

社交焦虑症通常出现在青少年时期,其症状往往与抑郁症和自杀倾向同时出现。了解青少年的社交焦虑症状是否先于抑郁和自杀意念的出现非常重要。威康信托基金会 NSPN(精神病学网络中的神经科学)研究在英国招募了 2397 名 14-24 岁的青少年参与一项前瞻性观察研究。在基线、1 年随访和 2 年随访期间,我们对参与者的社交焦虑、广泛焦虑、抑郁和自杀意念症状进行了评估。我们进行了多元线性回归分析和中介分析,以研究基线社交焦虑是否与2年自杀意念和抑郁症状(不包括自杀相关项目)有关,以及这些关联是否受1年抑郁症状的中介影响。多元线性回归分析结果表明,在控制基线预测变量后,基线社交焦虑症状与2年自杀意念(β = 0.07,p < 0.05,95% CI [0.02,0.12])和2年抑郁症状(β = 0.08,p < 0.05,95% CI [0.02,0.13])相关。此外,1 年抑郁症状对基线社交焦虑症状与 2 年自杀意念之间的关系(β = 0.04,95% CI [0.02,0.05])以及基线社交焦虑症状与 2 年抑郁症状之间的关系(β = 0.我们发现有证据表明,在非临床青少年中,基线社交焦虑症状通过 1 年抑郁症状与 2 年自杀意念和 2 年抑郁症状相关。这些结果可能会对有针对性的心理干预产生重要影响。
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Social anxiety symptoms and their relationship with suicidal ideation and depressive symptoms in adolescents: A prospective study
Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample.The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14–24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1‐year follow‐up, and 2‐year follow‐up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2‐year suicidal ideation and depressive symptoms (excluding suicide‐related items), and whether these associations were mediated by 1‐year depressive symptoms. The study was preregistered on the Open Science Framework.Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2‐year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2‐year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1‐year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2‐year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2‐year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates.We found evidence that baseline social anxiety symptoms were associated with 2‐year suicidal ideation and 2‐year depressive symptoms via 1‐year depressive symptoms in non‐clinical adolescents. These results may have important implications for targeted psychological interventions.
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