脂质体作为人体营养中生物活性化合物的载体

Foods Pub Date : 2024-06-09 DOI:10.3390/foods13121814
M. Rudzińska, A. Grygier, Geoffrey Knight, D. Kmiecik
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引用次数: 0

摘要

本文概述了有关脂质体结构和封装物质在食品技术和人类营养中的作用的文献资料。文章简要介绍了脂质体是如何产生的,以及它们是如何封装食品成分的,这些成分可以是单个化合物,也可以是植物提取物。脂质体的另一个非常有趣的应用是用作抗菌载体,以防止食品在储存过程中变质。将食品成分封装在脂质体中可以提高其生物利用率,这对于具有促进健康特性但生物利用率低的化合物尤为重要。人们尤其关注植物甾醇等化合物,它们能降低血液中的胆固醇水平,但在人体内的吸收率却很低。此外,还讨论了消费者对食品中脂质体的期望和相关法规。迄今为止,还没有进行过体内人体研究,以确定哪种封装方法对胃肠道的效果最好,以及哪种食品添加物质在食品储存和加工过程中最稳定。本文指出了在将脂质体引入食品之前需要进一步研究的领域。
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Liposomes as Carriers of Bioactive Compounds in Human Nutrition
This article provides an overview of the literature data on the role of liposomal structures and encapsulated substances in food technology and human nutrition. The paper briefly describes how liposomes are created and how they encapsulate food ingredients, which can either be individual compounds or plant extracts. Another very interesting application of liposomes is their use as antimicrobial carriers to protect food products from spoilage during storage. The encapsulation of food ingredients in liposomes can increase their bioavailability, which is particularly important for compounds with health-promoting properties but low bioavailability. Particular attention was paid to compounds such as phytosterols, which lower blood cholesterol levels but have very low absorption in the human body. In addition, consumer expectations and regulations for liposomes in food are discussed. To date, no in vivo human studies have been conducted to indicate which encapsulation methods give the best results for gastrointestinal effects and which food-added substances are most stable during food storage and processing. The paper identifies further lines of research that are needed before liposomes can be introduced into food.
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