Harry Budiman, Dhan Rasyidan, Arum Ma’rifatun Khikmah
{"title":"分析氮基质中二氧化碳标准混合气体的气相色谱法验证和稳定性研究","authors":"Harry Budiman, Dhan Rasyidan, Arum Ma’rifatun Khikmah","doi":"10.1007/s12647-024-00757-y","DOIUrl":null,"url":null,"abstract":"<div><p>Currently, precise and accurate measurements of CO<sub>2</sub> emissions are essential for obtaining valid and reliable monitoring data, which serve as the basis for decision-making by environmental policy makers. In this study, method validation was carried out to measure CO<sub>2</sub> at emission concentrations (1000 μmol/mol and 2.8% mol/mol) using gas chromatography with a thermal conductivity detector (GC-TCD). Various parameters of method validation, such as selectivity, limit of detection (LoD), limit of quantification (LoQ), accuracy, precision, linearity, and ruggedness, were investigated thoroughly. The results showed that the GC-TCD method demonstrated good repeatability and intermediate precision, with a % relative standard deviation less than 0.2%, while the bias method had a value between ± 2σ (σ: precision of laboratory result). The relative expanded uncertainty estimations are approximately 0.5% and 0.8% for CO<sub>2</sub> measurements of 2.8% mol/mol and 1000 µmol/mol, respectively. The validated in-house method of GC-TCD is found to be precise, accurate, and fit for the purpose of measuring CO<sub>2</sub> gases in the N<sub>2</sub> matrix and capable of quantifying CO<sub>2</sub> emission levels (1000 µmol/mol and 2.8% mol/mol).</p></div>","PeriodicalId":689,"journal":{"name":"MAPAN","volume":"39 4","pages":"787 - 798"},"PeriodicalIF":1.0000,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Method Validation of Gas Chromatography and Stability Study for Analysis of Standard Gas Mixtures of Carbon Dioxide in Nitrogen Matrix\",\"authors\":\"Harry Budiman, Dhan Rasyidan, Arum Ma’rifatun Khikmah\",\"doi\":\"10.1007/s12647-024-00757-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Currently, precise and accurate measurements of CO<sub>2</sub> emissions are essential for obtaining valid and reliable monitoring data, which serve as the basis for decision-making by environmental policy makers. In this study, method validation was carried out to measure CO<sub>2</sub> at emission concentrations (1000 μmol/mol and 2.8% mol/mol) using gas chromatography with a thermal conductivity detector (GC-TCD). Various parameters of method validation, such as selectivity, limit of detection (LoD), limit of quantification (LoQ), accuracy, precision, linearity, and ruggedness, were investigated thoroughly. The results showed that the GC-TCD method demonstrated good repeatability and intermediate precision, with a % relative standard deviation less than 0.2%, while the bias method had a value between ± 2σ (σ: precision of laboratory result). The relative expanded uncertainty estimations are approximately 0.5% and 0.8% for CO<sub>2</sub> measurements of 2.8% mol/mol and 1000 µmol/mol, respectively. The validated in-house method of GC-TCD is found to be precise, accurate, and fit for the purpose of measuring CO<sub>2</sub> gases in the N<sub>2</sub> matrix and capable of quantifying CO<sub>2</sub> emission levels (1000 µmol/mol and 2.8% mol/mol).</p></div>\",\"PeriodicalId\":689,\"journal\":{\"name\":\"MAPAN\",\"volume\":\"39 4\",\"pages\":\"787 - 798\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MAPAN\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12647-024-00757-y\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INSTRUMENTS & INSTRUMENTATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MAPAN","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s12647-024-00757-y","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}
Method Validation of Gas Chromatography and Stability Study for Analysis of Standard Gas Mixtures of Carbon Dioxide in Nitrogen Matrix
Currently, precise and accurate measurements of CO2 emissions are essential for obtaining valid and reliable monitoring data, which serve as the basis for decision-making by environmental policy makers. In this study, method validation was carried out to measure CO2 at emission concentrations (1000 μmol/mol and 2.8% mol/mol) using gas chromatography with a thermal conductivity detector (GC-TCD). Various parameters of method validation, such as selectivity, limit of detection (LoD), limit of quantification (LoQ), accuracy, precision, linearity, and ruggedness, were investigated thoroughly. The results showed that the GC-TCD method demonstrated good repeatability and intermediate precision, with a % relative standard deviation less than 0.2%, while the bias method had a value between ± 2σ (σ: precision of laboratory result). The relative expanded uncertainty estimations are approximately 0.5% and 0.8% for CO2 measurements of 2.8% mol/mol and 1000 µmol/mol, respectively. The validated in-house method of GC-TCD is found to be precise, accurate, and fit for the purpose of measuring CO2 gases in the N2 matrix and capable of quantifying CO2 emission levels (1000 µmol/mol and 2.8% mol/mol).
期刊介绍:
MAPAN-Journal Metrology Society of India is a quarterly publication. It is exclusively devoted to Metrology (Scientific, Industrial or Legal). It has been fulfilling an important need of Metrologists and particularly of quality practitioners by publishing exclusive articles on scientific, industrial and legal metrology.
The journal publishes research communication or technical articles of current interest in measurement science; original work, tutorial or survey papers in any metrology related area; reviews and analytical studies in metrology; case studies on reliability, uncertainty in measurements; and reports and results of intercomparison and proficiency testing.