{"title":"碳纳米载体在生物医学应用中的安全性:石墨烯及其衍生物的生物相容性","authors":"A. Botin, M.G.H. Rizk, T. Popova, A. Cordova","doi":"10.29039/rusjbpc.2023.0650","DOIUrl":null,"url":null,"abstract":"The article considers one of the most important factors allowing to determine the possibility of wide and safe use of graphene nanoobjects in modern biomedicine - this is the biocompatibility factor, namely, the interaction of a graphene-containing substance with a given part of the body, which is realized at different scales and at different levels of organization of living matter. Graphene and its derivatives have shown exceptional properties and potential for various applications. While graphene derivatives as graphene-oxide (GO), reduced graphene-oxide (rGO), few-layers graphene (FLG), and multi-layers graphene (MLG) exhibit similar properties to graphene, more research is needed to address scalability and cost-effectiveness for practical applications. In tissue engineering, graphene-based materials have shown promise in scaffolds, biosensors, and drug delivery systems, but optimizing biocompatibility and functionalization strategies are crucial for safe and effective use. This work is a try to better understanding the complex interactions between graphene and biological systems, including cells, tissues, and organs, which is necessary for future research and expanding the use of graphene in biomedical applications.","PeriodicalId":169374,"journal":{"name":"Russian Journal of Biological Physics and Chemisrty","volume":"36 1‐2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SAFETY OF CARBON NANOCARRIERS IN BIOMEDICAL APPLICATIONS: BIOCOMPATIBILITY OF GRAPHENE AND ITS DERIVATIVES\",\"authors\":\"A. Botin, M.G.H. Rizk, T. Popova, A. Cordova\",\"doi\":\"10.29039/rusjbpc.2023.0650\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The article considers one of the most important factors allowing to determine the possibility of wide and safe use of graphene nanoobjects in modern biomedicine - this is the biocompatibility factor, namely, the interaction of a graphene-containing substance with a given part of the body, which is realized at different scales and at different levels of organization of living matter. Graphene and its derivatives have shown exceptional properties and potential for various applications. While graphene derivatives as graphene-oxide (GO), reduced graphene-oxide (rGO), few-layers graphene (FLG), and multi-layers graphene (MLG) exhibit similar properties to graphene, more research is needed to address scalability and cost-effectiveness for practical applications. In tissue engineering, graphene-based materials have shown promise in scaffolds, biosensors, and drug delivery systems, but optimizing biocompatibility and functionalization strategies are crucial for safe and effective use. This work is a try to better understanding the complex interactions between graphene and biological systems, including cells, tissues, and organs, which is necessary for future research and expanding the use of graphene in biomedical applications.\",\"PeriodicalId\":169374,\"journal\":{\"name\":\"Russian Journal of Biological Physics and Chemisrty\",\"volume\":\"36 1‐2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Biological Physics and Chemisrty\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29039/rusjbpc.2023.0650\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Biological Physics and Chemisrty","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29039/rusjbpc.2023.0650","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SAFETY OF CARBON NANOCARRIERS IN BIOMEDICAL APPLICATIONS: BIOCOMPATIBILITY OF GRAPHENE AND ITS DERIVATIVES
The article considers one of the most important factors allowing to determine the possibility of wide and safe use of graphene nanoobjects in modern biomedicine - this is the biocompatibility factor, namely, the interaction of a graphene-containing substance with a given part of the body, which is realized at different scales and at different levels of organization of living matter. Graphene and its derivatives have shown exceptional properties and potential for various applications. While graphene derivatives as graphene-oxide (GO), reduced graphene-oxide (rGO), few-layers graphene (FLG), and multi-layers graphene (MLG) exhibit similar properties to graphene, more research is needed to address scalability and cost-effectiveness for practical applications. In tissue engineering, graphene-based materials have shown promise in scaffolds, biosensors, and drug delivery systems, but optimizing biocompatibility and functionalization strategies are crucial for safe and effective use. This work is a try to better understanding the complex interactions between graphene and biological systems, including cells, tissues, and organs, which is necessary for future research and expanding the use of graphene in biomedical applications.