迷走神经刺激治疗难治性癫痫

Q4 Medicine Ugeskrift for laeger Pub Date : 2024-06-03 DOI:10.61409/v10230638

Per Jensen, Ioannis Tsiropoulos

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引用次数: 0

摘要

约 40% 的新发癫痫是药物难治性癫痫。如果不能选择癫痫手术或手术失败，可以考虑迷走神经刺激（VNS）。据报道，50%-56% 的患者的癫痫发作频率减少了 50%以上。新型号的特点提供了更多优化治疗的可能性。副作用包括声音嘶哑、咳嗽和呼吸困难。建议患有睡眠呼吸暂停或肺部疾病的患者谨慎使用。VNS 在磁共振成像方面有特定的局限性。本综述概述了丹麦的 VNS 治疗情况，并讨论了未来的挑战。

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Vagus nerve stimulation for the treatment of treatment-refractory epilepsy

About 40 % of new-onset epilepsy is drug refractory. If epilepsy surgery is not an option or fails, vagal nerve stimulation (VNS) can be considered. VNS efficacy is reported as more than 50 % seizure frequency reduction in 50-56 % of patients. Features in the newer models offer additional treatment optimization possibilities. Side effects include hoarseness, cough, and dyspnoea. Caution is advised for patients with sleep apnoea or lung disease. VNS has specific limitations concerning MRI. This review presents an overview of VNS treatment in Denmark and discusses future challenges.

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来源期刊

Ugeskrift for laeger Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

345

期刊介绍： The Ulster Medical Journal is an international general medical journal with contributions on all areas of medical and surgical specialties relevant to a general medical readership. It retains a focus on material relevant to the health of the Northern Ireland population. The Honorary Editor would welcome offers of papers for publication. Prospective authors are invited to read the notice to contributors.

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