阿曼实体瘤癌症患者念珠菌血症中格拉布氏念珠菌占主导地位：一项回顾性研究

IF 1.5 Q4 INFECTIOUS DISEASES IJID regions Pub Date : 2024-06-15 DOI:10.1016/j.ijregi.2024.100389

Bassem Awada , Aref Zribi , Ahmad Ghoche , Hasan Al-Sayegh , Manyando Milupi , Boris Itkin , Khalid Al-Baimani , Jorge Abarca

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摘要

方法为了解决这一问题，我们于 2021 年 10 月至 2023 年 10 月在苏丹卡布斯综合癌症研究中心进行了一项回顾性研究。结果我们的研究在 26 名癌症患者中发现了 27 例念珠菌血症，每 1000 名入院患者中的发病率为 4.9。非白念珠菌病（NAC）的发病率高于白念珠菌病（70.37% vs 29.62%），主要的NAC菌种是格拉布氏念珠菌（n = 10；37%）。30 天死亡率为 40.7%，NAC 与白念珠菌之间无显著差异，但重症患者的死亡率明显更高（P = 0.03）。

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Predominance of Candida glabrata in candidemia among patients with solid tumor cancer in Oman: A retrospective study

Objectives

Candida species frequently cause bloodstream infections; however, there is a lack of epidemiological studies on candidemia in Oman.

Methods

To address this, we conducted a retrospective study at Sultan Qaboos Comprehensive Cancer and Research Center from October 2021 to October 2023.

Results

Our study identified 27 episodes of candidemia among 26 patients with cancer, with an incidence of 4.9 per 1000 admissions. Non-albicans Candida (NAC) prevailed over C. albicans (70.37% vs 29.62%), with C. glabrata as the predominant NAC species (n = 10; 37%). The 30-day mortality rate was 40.7%, showing no significant difference between NAC and C. albicans but was notably higher in critically ill patients (P = 0.03).