{"title":"通过 DIET 交叉链接预防抑郁障碍:饮食、肠道微生物群、酶和代谢特征","authors":"Yuye Gao, Tingting Zhou","doi":"10.1016/j.tifs.2024.104596","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Depressive disorder affects more than 350 million people worldwide, an increase of 18% over the past decade. Recent research suggests a link between dietary patterns and depression, with diets rich in seafood, vegetables, fruits and nuts may reduce the risk of depression, while an unbalanced diet could affect intestinal microbiota and promote the development of depression.</p></div><div><h3>Scope and approach</h3><p>In this review, a new strategy was proposed namely DIET crosslink (Depression and Diet, Intestinal microbiota, Enzyme and Traits of metabolism) to describe diet altering the enzymes produced by intestinal microbiota that influence traits of metabolism to treatment for depression. Patients exhibit changes in the abundance and composition of the gut microbiota, which produce numerous enzymes involved in the digestion and metabolism of dietary components, affect the production and absorption of exogenous metabolites by the body, affect the bioavailability of food and the progression of depression.</p></div><div><h3>Key findings and conclusions</h3><p>DIET crosslink strategy underscores the significance of specific enzymes and metabolites in personalized depression treatment, providing a route to individualized care. Besides, this dynamic approach breaks from static studies, exploring the intricate interplay among diet, microbiota, enzymes, metabolism and disease, which provides a new perspective on researching how dietary influences impact changes in intestinal microbiota for disease treatment.</p></div>","PeriodicalId":441,"journal":{"name":"Trends in Food Science & Technology","volume":null,"pages":null},"PeriodicalIF":15.1000,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Depressive disorder prevention by DIET crosslink: Diet, intestinal microbiota, enzyme and traits of metabolism\",\"authors\":\"Yuye Gao, Tingting Zhou\",\"doi\":\"10.1016/j.tifs.2024.104596\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Depressive disorder affects more than 350 million people worldwide, an increase of 18% over the past decade. Recent research suggests a link between dietary patterns and depression, with diets rich in seafood, vegetables, fruits and nuts may reduce the risk of depression, while an unbalanced diet could affect intestinal microbiota and promote the development of depression.</p></div><div><h3>Scope and approach</h3><p>In this review, a new strategy was proposed namely DIET crosslink (Depression and Diet, Intestinal microbiota, Enzyme and Traits of metabolism) to describe diet altering the enzymes produced by intestinal microbiota that influence traits of metabolism to treatment for depression. Patients exhibit changes in the abundance and composition of the gut microbiota, which produce numerous enzymes involved in the digestion and metabolism of dietary components, affect the production and absorption of exogenous metabolites by the body, affect the bioavailability of food and the progression of depression.</p></div><div><h3>Key findings and conclusions</h3><p>DIET crosslink strategy underscores the significance of specific enzymes and metabolites in personalized depression treatment, providing a route to individualized care. Besides, this dynamic approach breaks from static studies, exploring the intricate interplay among diet, microbiota, enzymes, metabolism and disease, which provides a new perspective on researching how dietary influences impact changes in intestinal microbiota for disease treatment.</p></div>\",\"PeriodicalId\":441,\"journal\":{\"name\":\"Trends in Food Science & Technology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":15.1000,\"publicationDate\":\"2024-06-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Food Science & Technology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0924224424002723\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Food Science & Technology","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0924224424002723","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Depressive disorder prevention by DIET crosslink: Diet, intestinal microbiota, enzyme and traits of metabolism
Background
Depressive disorder affects more than 350 million people worldwide, an increase of 18% over the past decade. Recent research suggests a link between dietary patterns and depression, with diets rich in seafood, vegetables, fruits and nuts may reduce the risk of depression, while an unbalanced diet could affect intestinal microbiota and promote the development of depression.
Scope and approach
In this review, a new strategy was proposed namely DIET crosslink (Depression and Diet, Intestinal microbiota, Enzyme and Traits of metabolism) to describe diet altering the enzymes produced by intestinal microbiota that influence traits of metabolism to treatment for depression. Patients exhibit changes in the abundance and composition of the gut microbiota, which produce numerous enzymes involved in the digestion and metabolism of dietary components, affect the production and absorption of exogenous metabolites by the body, affect the bioavailability of food and the progression of depression.
Key findings and conclusions
DIET crosslink strategy underscores the significance of specific enzymes and metabolites in personalized depression treatment, providing a route to individualized care. Besides, this dynamic approach breaks from static studies, exploring the intricate interplay among diet, microbiota, enzymes, metabolism and disease, which provides a new perspective on researching how dietary influences impact changes in intestinal microbiota for disease treatment.
期刊介绍:
Trends in Food Science & Technology is a prestigious international journal that specializes in peer-reviewed articles covering the latest advancements in technology, food science, and human nutrition. It serves as a bridge between specialized primary journals and general trade magazines, providing readable and scientifically rigorous reviews and commentaries on current research developments and their potential applications in the food industry.
Unlike traditional journals, Trends in Food Science & Technology does not publish original research papers. Instead, it focuses on critical and comprehensive reviews to offer valuable insights for professionals in the field. By bringing together cutting-edge research and industry applications, this journal plays a vital role in disseminating knowledge and facilitating advancements in the food science and technology sector.