Tamara Dörr, Sabine Güsewell, Domenica Flury, Maria Süveges, Camille Beatrice Gaza Valera, Sara Botero-Mesa, Marie-Céline Zanella, Anne Iten, Carlo Balmelli, Nicolas Troillet, Sarah Tschudin-Sutter, Peter W Schreiber, Philipp Jent, Lauro Damonti, Rami Sommerstein, Lea Portmann, Danielle Vuichard-Gysin, Alexia Cusini, Yvonne Nussbaumer-Ochsner, Ulrich Heininger, Christoph Berger, Petra Zimmermann, Céline Gardiol, Olivia Keiser, Matthias Schlegel, Philipp Kohler, Stefan P Kuster
{"title":"BA.4/5疫情期间瑞士急症护理医院中机构掩蔽政策与医护人员相关 SARS-CoV-2 感染的关系（CH-SUR 研究）：一项回顾性观察研究。","authors":"Tamara Dörr, Sabine Güsewell, Domenica Flury, Maria Süveges, Camille Beatrice Gaza Valera, Sara Botero-Mesa, Marie-Céline Zanella, Anne Iten, Carlo Balmelli, Nicolas Troillet, Sarah Tschudin-Sutter, Peter W Schreiber, Philipp Jent, Lauro Damonti, Rami Sommerstein, Lea Portmann, Danielle Vuichard-Gysin, Alexia Cusini, Yvonne Nussbaumer-Ochsner, Ulrich Heininger, Christoph Berger, Petra Zimmermann, Céline Gardiol, Olivia Keiser, Matthias Schlegel, Philipp Kohler, Stefan P Kuster","doi":"10.1186/s13756-024-01422-4","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In the initial phase of the SARS-CoV-2 pandemic, masking has been widely accepted in healthcare institutions to mitigate the risk of healthcare-associated infection. Evidence, however, is still scant and the role of masks in preventing healthcare-associated SARS-CoV-2 acquisition remains unclear.We investigated the association of variation in institutional mask policies with healthcare-associated SARS-CoV-2 infections in acute care hospitals in Switzerland during the BA.4/5 2022 wave.</p><p><strong>Methods: </strong>SARS-CoV-2 infections in hospitalized patients between June 1 and September 5, 2022, were obtained from the \"Hospital-based surveillance of COVID-19 in Switzerland\"-database and classified as healthcare- or community-associated based on time of disease onset. Institutions provided information regarding institutional masking policies for healthcare workers and other prevention policies. The percentage of healthcare-associated SARS-CoV-2 infections was calculated per institution and per type of mask policy. The association of healthcare-associated SARS-CoV-2 infections with mask policies was tested using a negative binominal mixed-effect model.</p><p><strong>Results: </strong>We included 2'980 SARS-CoV-2 infections from 13 institutions, 444 (15%) were classified as healthcare-associated. Between June 20 and June 30, 2022, six (46%) institutions switched to a more stringent mask policy. The percentage of healthcare-associated infections subsequently declined in institutions with policy switch but not in the others. In particular, the switch from situative masking (standard precautions) to general masking of HCW in contact with patients was followed by a strong reduction of healthcare-associated infections (rate ratio 0.39, 95% CI 0.30-0.49). In contrast, when compared across hospitals, the percentage of health-care associated infections was not related to mask policies.</p><p><strong>Conclusions: </strong>Our findings suggest switching to a more stringent mask policy may be beneficial during increases of healthcare-associated SARS-CoV-2 infections at an institutional level.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"13 1","pages":"64"},"PeriodicalIF":4.8000,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184728/pdf/","citationCount":"0","resultStr":"{\"title\":\"Association of institutional masking policies with healthcare-associated SARS-CoV-2 infections in Swiss acute care hospitals during the BA.4/5 wave (CH-SUR study): a retrospective observational study.\",\"authors\":\"Tamara Dörr, Sabine Güsewell, Domenica Flury, Maria Süveges, Camille Beatrice Gaza Valera, Sara Botero-Mesa, Marie-Céline Zanella, Anne Iten, Carlo Balmelli, Nicolas Troillet, Sarah Tschudin-Sutter, Peter W Schreiber, Philipp Jent, Lauro Damonti, Rami Sommerstein, Lea Portmann, Danielle Vuichard-Gysin, Alexia Cusini, Yvonne Nussbaumer-Ochsner, Ulrich Heininger, Christoph Berger, Petra Zimmermann, Céline Gardiol, Olivia Keiser, Matthias Schlegel, Philipp Kohler, Stefan P Kuster\",\"doi\":\"10.1186/s13756-024-01422-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>In the initial phase of the SARS-CoV-2 pandemic, masking has been widely accepted in healthcare institutions to mitigate the risk of healthcare-associated infection. Evidence, however, is still scant and the role of masks in preventing healthcare-associated SARS-CoV-2 acquisition remains unclear.We investigated the association of variation in institutional mask policies with healthcare-associated SARS-CoV-2 infections in acute care hospitals in Switzerland during the BA.4/5 2022 wave.</p><p><strong>Methods: </strong>SARS-CoV-2 infections in hospitalized patients between June 1 and September 5, 2022, were obtained from the \\\"Hospital-based surveillance of COVID-19 in Switzerland\\\"-database and classified as healthcare- or community-associated based on time of disease onset. Institutions provided information regarding institutional masking policies for healthcare workers and other prevention policies. The percentage of healthcare-associated SARS-CoV-2 infections was calculated per institution and per type of mask policy. The association of healthcare-associated SARS-CoV-2 infections with mask policies was tested using a negative binominal mixed-effect model.</p><p><strong>Results: </strong>We included 2'980 SARS-CoV-2 infections from 13 institutions, 444 (15%) were classified as healthcare-associated. Between June 20 and June 30, 2022, six (46%) institutions switched to a more stringent mask policy. The percentage of healthcare-associated infections subsequently declined in institutions with policy switch but not in the others. In particular, the switch from situative masking (standard precautions) to general masking of HCW in contact with patients was followed by a strong reduction of healthcare-associated infections (rate ratio 0.39, 95% CI 0.30-0.49). In contrast, when compared across hospitals, the percentage of health-care associated infections was not related to mask policies.</p><p><strong>Conclusions: </strong>Our findings suggest switching to a more stringent mask policy may be beneficial during increases of healthcare-associated SARS-CoV-2 infections at an institutional level.</p>\",\"PeriodicalId\":7950,\"journal\":{\"name\":\"Antimicrobial Resistance and Infection Control\",\"volume\":\"13 1\",\"pages\":\"64\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184728/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Antimicrobial Resistance and Infection Control\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s13756-024-01422-4\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Antimicrobial Resistance and Infection Control","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13756-024-01422-4","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Association of institutional masking policies with healthcare-associated SARS-CoV-2 infections in Swiss acute care hospitals during the BA.4/5 wave (CH-SUR study): a retrospective observational study.
Background: In the initial phase of the SARS-CoV-2 pandemic, masking has been widely accepted in healthcare institutions to mitigate the risk of healthcare-associated infection. Evidence, however, is still scant and the role of masks in preventing healthcare-associated SARS-CoV-2 acquisition remains unclear.We investigated the association of variation in institutional mask policies with healthcare-associated SARS-CoV-2 infections in acute care hospitals in Switzerland during the BA.4/5 2022 wave.
Methods: SARS-CoV-2 infections in hospitalized patients between June 1 and September 5, 2022, were obtained from the "Hospital-based surveillance of COVID-19 in Switzerland"-database and classified as healthcare- or community-associated based on time of disease onset. Institutions provided information regarding institutional masking policies for healthcare workers and other prevention policies. The percentage of healthcare-associated SARS-CoV-2 infections was calculated per institution and per type of mask policy. The association of healthcare-associated SARS-CoV-2 infections with mask policies was tested using a negative binominal mixed-effect model.
Results: We included 2'980 SARS-CoV-2 infections from 13 institutions, 444 (15%) were classified as healthcare-associated. Between June 20 and June 30, 2022, six (46%) institutions switched to a more stringent mask policy. The percentage of healthcare-associated infections subsequently declined in institutions with policy switch but not in the others. In particular, the switch from situative masking (standard precautions) to general masking of HCW in contact with patients was followed by a strong reduction of healthcare-associated infections (rate ratio 0.39, 95% CI 0.30-0.49). In contrast, when compared across hospitals, the percentage of health-care associated infections was not related to mask policies.
Conclusions: Our findings suggest switching to a more stringent mask policy may be beneficial during increases of healthcare-associated SARS-CoV-2 infections at an institutional level.
期刊介绍：
Antimicrobial Resistance and Infection Control is a global forum for all those working on the prevention, diagnostic and treatment of health-care associated infections and antimicrobial resistance development in all health-care settings. The journal covers a broad spectrum of preeminent practices and best available data to the top interventional and translational research, and innovative developments in the field of infection control.
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